Studying physical activity and sitting time in adults with cystic fibrosis
Observes how active adults with cystic fibrosis are and how much time they spend sitting.
Plain-language title generated from the registry record
Registry title: Physical Activity Profile and Sedentary Behaviour in Adults With Cystic Fibrosis
Key facts
- Where
- Pierre-Bénite, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06507956, who can take part
Where in France
- Hopital Lyon SudPierre-Bénite, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospices Civils de Lyon
- Trial code
- NCT06507956
- Record updated
- 21 November 2025
- Original description
Cystic fibrosis is a multisystem genetic disease whose severity, linked to the nature of the mutation in the gene carried, is linked to respiratory impairment, which determines the vital prognosis.Read full original descriptionShow less
Physical Activity Profile and Sedentary Behaviour in Adults With Cystic Fibrosis
Cystic fibrosis is a multisystem genetic disease whose severity, linked to the nature of the mutation in the gene carried, is linked to respiratory impairment, which determines the vital prognosis.
Considerable progress has been made in the management of this disease, amplified in recent years by the arrival of CFTR (cystic fibrosis transmembrane conductance regulator) modulator drugs, and in particular the triple treatment combination of elexacaftor-tezacaftor-ivacaftor (ETI). This modulator therapy improves clinical condition, particularly respiratory, and transforms quality of life and prognosis for some patients. Faced with this clinical improvement, practices and care paths are adapting. Professionals will have to cope with the emergence of new clinical conditions linked to the ageing of this at-risk population and the functional decline due to a sedentary lifestyle and age.
The working hypothesis is that a better understanding of the physical activity and sedentary lifestyle profiles of the adult population with cystic fibrosis, and in particular the characterization of the profile of inactive and high sedentary patients under ETI, will enable us to identify and target patients whose lifestyle habits reflect a greater health risk, and for whom care by rehabilitators and adapted physical activity (APA) teachers and personalized advice could be put in place.
The aim of this study is to characterize the physical activity and sedentary profile of adults with cystic fibrosis.
ACTIVMUCO is an observational, cross-sectional, single-center study. A subgroup of adults with high sedentary and inactive under ETI will be studied more specifically by actimetry (prospective follow-up) and interview.
Inclusion: Patients (male or female) of legal age,; Patients with cystic fibrosis (CF) regularly followed at Hôpital Lyon Sud's cystic fibrosis center, who volunteered to take part in the study.
Exclusion: Persons under psychiatric care; People who, due to the presence of co-morbidities, do not have motor and cognitive skills compatible with independent walking or orthostatic physical activity; People whose clinical situation contraindicates the practice of adapted physical activity; Pregnant women; People who do not have the intellectual or linguistic capacity to understand the questionnaires; Persons deprived of their liberty by judicial or administrative decision; Persons admitted to a health or social establishment for purposes other than research; Adults under legal protection (guardianship, curatorship); Persons not affiliated to a social security scheme or beneficiaries of a similar scheme.