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Testing a brain implant to control tablets in people with paralysis

Tests a brain implant that reads brain signals to run tablet apps.

Plain-language title generated from the registry record
Registry title: Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Key facts

Where
Boston, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT06511934, who can take part

Where in United States

  • Masssachusetts General HospitalBoston, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Leigh R. Hochberg, MD, PhD.
Trial code
NCT06511934
Record updated
26 October 2026
Original description
People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert. In this project, the investigators seek to further translate knowledge about interpreting brain signals related to movement, and to further develop an intracortical brain-computer interface (iBCI) that could restore rapid and intuitive use of communication apps on tablet computers by people with paralysis.Read full original descriptionShow less

Intuitive, Complete Neural Control of Tablet Computers for Communication

People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert. In this project, the investigators seek to further translate knowledge about interpreting brain signals related to movement, and to further develop an intracortical brain-computer interface (iBCI) that could restore rapid and intuitive use of communication apps on tablet computers by people with paralysis.

Inclusion: Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy, amyotrophic lateral sclerosis or other motor neuron disorders; Complete or incomplete tetraplegia (quadriplegia); Must live within a three-hour drive of the Study site; Prior enrollment in BrainGate2 clinical trial (NCT00912041).

Exclusion: Chronic oral or intravenous steroids or immunosuppressive therapy; Visual impairment such that extended viewing of a computer monitor would be difficult even with ordinary corrective lenses; Other serious disease or disorder that could seriously affect ability to participate in the study; (There are additional exclusion criteria).

ClinicalTrials.gov NCT06511934