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Increasing the Repertoire of Intermuscular Co-ordination Post Stroke Through EMG-Guided Human-Machine Interaction

Key facts

Where
Houston, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 75 years old?

Source: NCT06523335, who can take part

Where in United States

  • University of HoustonHouston, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University of Houston
Trial code
NCT06523335
Record updated
4 May 2026
Original description
The purposes of this study include:Read full original descriptionShow less

Intermuscular Coordination as a Novel Clinical Target for Stroke Neurorehabilitation

The purposes of this study include:

1. - To identify whether features of aberrant intermuscular coordination patterns can be used to predict motor impairment after stroke. 2. - To test whether muscle synergies are malleable to a non-invasive EMG-guided exercise that induces changes in intermuscular coordination of upper extremity muscles after stroke.

Inclusion: Male or female whose age range between 40 and 75; no known neurological injuries; male or female hemiparetic chronic stroke survivors; age ranging between 40-75 year; with single unilateral ischemic or hemorrhagic middle cerebral artery stroke; neurologically stable for >6 months; have an expectation that current medication will be maintained without changes for at least 3 months. Stable use of anti-spasticity medication (e.g., baclofen, diazepam, tizanidine) is accepted; without severe spasticity (Modified Ashworth (MA) <4); have not received botulinum toxin on the impaired arm within 3 months.

Exclusion: have an orthopedic disorder involving upper limbs; have a history of any neurologic disease; have any history of epilepsy of the potential participants and/or their family members; have an orthopedic disorder involving upper limbs; cognitive impairment sufficient to interfere with informed consent or successful completion of the protocol (Montreal Cognitive Assessment (MoCA) score < 26); a history of another neurologic disease; are unable to consent; are pregnant; anesthesia of joint position sense in upper limbs; are pregnant or have a chance that they might be (self-reported).

ClinicalTrials.gov NCT06523335