Imaging kidney tumors to measure how stiff or soft they are
Compares imaging scans that measure kidney tumor stiffness, including MR-elastography and ultrasound, in adults.
Key facts
- Who runs it
- University Hospital, Bordeaux
- Where
- Bordeaux, FranceSee the site
- Trial code
- Registry title
- Rein 3D PRINT MECHANICS
- Status
- Recruiting
- People taking part
- 50 people, planned
- Started
- 7 Mar 2025
- Expected to end
- 7 May 2027
- Type of study
- Interventional
- Treatments tested
- MR-elastography exam
- Ultrasound exam
- Record updated
- 14 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who are scheduled for kidney removal surgery (nephrectomy) because of a kidney tumor at Bordeaux University Hospital. It studies how imaging shows how stiff or soft kidney tissue is.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- A kidney tumor treated by nephrectomy. Cystic or necrotic tumors can join only if the solid part is 2 cm (0.8 in) or larger.
- Earlier treatment
- No biopsy in the 15 days before the MRI, CT and ultrasound scans.
Main reasons for not taking part
- Pregnant or breast-feeding women
- Cannot have an MRI, or cannot have the gadoline contrast agent
- Body mass index of 30 kg/m² or more
- Thoracolumbar arthrodesis (spinal fusion) material
- Ascites, or a person under legal protection
The registry criteria, word for word
Show all 17 criteriaShow less
Who can take part
- Adult patients (≥ 18 years of age)
- Scheduled for surgical management with nephrectomy for kidney tumor in the urology department of Bordeaux University Hospital
- CT scan available or scheduled for surgery
- Consent expressed for integration of the UroCCR database
- Expressed consent for participation in the Rein 3D Print Mechanics study
- Patients affiliated or benefiting from social security system
Who cannot take part
- Biopsy performed within 15 days prior to MRI, CT and ultrasound scans (risk of artifactual alteration, via iatrogenic hemorrhagic changes, of the biomechanical properties of the renal tumor and parenchyma)
- - Pregnant or breast-feeding women
- Contraindication to MRI (Magnetic Resonance Imaging)
- Contraindication to injection of gadoline contrast agents
- Presence of thoracolumbar arthrodesis material
- Obese patient (body mass index ≥ 30 kg/m²)
- Cystic renal tumors with solid component (corresponding to either parietal thickening or tumor bud) < 2 cm
- Necrotic renal tumors with solid component (corresponding to either parietal thickening or tumor bud) < 2 cm
- Ascites
- Person under legal protection
- Difficulty understanding and expressing in French
Where in France
- CHU de BordeauxBordeaux, FranceContact: Eva FOURAGE, DrTaking people
About the trial
What the trial wants to find out
The goal of this innovative project is to evaluate the correspondence between several imaging modalities for characterizing the elasticity of healthy and pathological renal tissue which could help improve the realism of 3D prints used by urological surgeons and allow the identification of new, complementary imaging biomarkers. The main objective is to develop a predictive model of the biomechanical properties of normal and pathological kidney tissue, as assessed by the reference method (Magnetic Resonance (MR)-elastography).
The group in the trial
- Patient with kidney cancer surgeryTreatment being tested
the patients will have an additionnal MRI elastography and Ultrasound exams for the research. The exams will be performed between the inclusion of the patient and the day before the surgery. Both exams are non-invasive, without radiation
Treatment: MR-elastography exam and Ultrasound exam
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Multimodal Imaging of the Biomechanical Properties of Kidney Tumors: Feasibility, Inter-modality Correspondence and Diagnostic Value
- Plain-language title
- Imaging kidney tumors to measure how stiff or soft they areGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Publications
- Record updated
- 14 April 2026