Fibromyalgia and Small Fiber Neuropathy

Who can take part

• patients over 18 years of age with no age limit -
• having given their signed consent to take part in the study
• affiliated to the French social security system
• able to be followed for the entire duration of the study
• reading and understanding French
• accepting the principle of the study and able to comply with its conditions
• suffering from chronic pain for at least six months of at least moderate intensity (≥ 4/10)
• fibromyalgia detected by the FiRST questionnare and defined by the revised diagnostic criteria of the WHO or chronic nociceptive or nociplastic pain without associated fibromyalgia
• chronic pain for at least 6 months of at least moderate intensity (≥ 4/10)
• untreated or with stable analgesic treatment for at least 2 weeks prior to inclusion- normal neurological examination at inclusion

Who cannot take part

• uncontrolled chronic pathology such as : morbid obesity, sleep apnea, uncontrolled hypertension, etc. - psychosis, previous suicide attempt
• drug or psychoactive substance abuse
• cancer for less than 2 years
• known cause of small-fiber neuropathy such as diabetes, systemic disease, hypothyroidism, alcohol, renal failure, genetic disease
• cognitive or psychological disorders incompatible with compliance with and/or understanding of the protocol
• litigation or compensation-seeking
• clinical or EMG neuropathy
• peripheral or central nervous system pathology with or without associated neuropathic pain
• participation in another biomedical research protocol