Effects of Ultrasound-guided Genicular Nerve Block in Knee Osteoarthritis Patients on Proprioception and Static Balance
Key facts
- Who runs it
- Ankara City Hospital Bilkent
- Where
- Türkiye1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 22 people enrolled
- Started
- 1 Jun 2024
- Ended
- 14 Jul 2024
- Type of study
- Interventional
- Treatments tested
- Genicular blocks (dexamethazone and lidocaine)
- Record updated
- 30 July 2024
Who can take part
- Age
- 50 years to 70 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Chronic knee pain more than >3 according to visual analog scale (VAS) and difficulty in function more than 3 months
- Grade 2-3 KOA according to the Kellgren -Lawrence radiological grading system
- No significant improvement in response to conservative treatments such as analgesics and physiotherapy
Who cannot take part
- Presence of intra-articular or peri-articular injection such as hyaluronic acids, corticosteroids or collagen supplements at last 6 months
- History of trauma, fractures, malignencies, surgery and inflammatory diseases of knee
- Allergies of pharmacological agents using during procedure (lidocaine)
- Other neurologic or rheumatological conditions that may lead vertigo or vestibular disfunction or presence of impairment in proprioception such as polineuropathy
- Presence of diabetes mellitus due to risk of small fiber neuropathy
- Cognitive impairment and uncontrolled systemic conditions
- Limitation of range of motion in unilaterally and/or bilaterally in knee joint
This trial has no sites in United States.
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About the trial
What the trial wants to find out
Genicular nerve block (GNB) is a novel and promising interventional method for pain in knee osteoarthritis (KOA). However ,it contains afferent fibers that receive impulses from proprioceptive and deep sensory receptors located in the joint capsule, ligaments, muscles, tendons and periosteum. These proprioceptive stimuli are effective on joint position and biomechanics, protect the joint from injuries and help maintain balance. This study aims to evaluate Pproprioception and static balance after ultrasound-guided GNB in patients with knee osteoarthritis.
The group in the trial
- Genicular blocksOther group
Genicular blocks were applied bilaterally by another physiatrist who was experienced in ultrasonographic (US) interventional procedures more than 5 years. Total of 6mL solution consisting of 0.5 mg/2mL dexamethazone and 4mL %1 lidocaine for three branches of genicular nerves (superomedial, superolateral and inferomedial branches) was divided into three branches for each knee. Total of 12 mL solution was applied for each patient. Antiseptic precautions were taken, sterile environment was prepared. A 5-12 MHz linear probe (Loqiq P5, GE Medical systems) was used for all US evaluations. The probe was positioned in line with the femur shaft. Firstly to find the superomedial genicular nerve, probe was moved to the junction of femur shaft and medial femoral condyle. Color doppler was used to clarify superomedial genicular artery and 2mL injection solution was applied around the pulsatile artery region.
Treatment: Genicular blocks (dexamethazone and lidocaine)
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 30 July 2024