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Pressure pain, balance and leg strength in children with sickle cell anemia

Measures pain tolerance, balance and leg strength in children with sickle cell anemia.

Plain-language title generated from the registry record
Registry title: Pressure Pain Tolerance in Relation to Balance and Strength in Children

Key facts

Where
Giza, EgyptSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 9 and 14 years old?

Source: NCT06529874, who can take part

Where in Egypt

  • El-Tahrir st.- in front of Ben El-Sarayat, Ad Doqi Al Giza, Giza GovernateGiza, EgyptTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Adly A Adam
Trial code
NCT06529874
Record updated
1 April 2025
Original description
Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent. This can cause pain and tissue damage. Significant decrease in exercise capacity was seen in sickle cell anemic children. In the absence of a guidelines that can guide the prescription of exercise in SCD children. This study is a step for determine the forms of prescription of pain on the balance and muscle strength to build up in future studies a safety of physical exercises for children with sickle cell anemia and improve their functional abilities.Read full original descriptionShow less

Pressure Pain Tolerance in Relation to Balance and Strength in Children With Sickle Cell Anemia

Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent. This can cause pain and tissue damage. Significant decrease in exercise capacity was seen in sickle cell anemic children. In the absence of a guidelines that can guide the prescription of exercise in SCD children. This study is a step for determine the forms of prescription of pain on the balance and muscle strength to build up in future studies a safety of physical exercises for children with sickle cell anemia and improve their functional abilities.

Inclusion: Age range range was 9-14 years old; Could follow given instructions; Children with Sickle cell anemia were medically stable, and take their medications regularly; Children with Sickle cell anemia had experience of chronic pain that lasts more than 6 months; All children with Sickle cell anemia have average weight, height, and body mass index based on their age percentiles; All normal healthy children did not participating in regular sport activities, particularly including lower limb strengthening.

Exclusion: Recent thoracoabdominal surgery; Defined cardiovascular or respiratory disorders; Renal failure; Myocardial infarction, mainly within last month; Unstable angina; Thoracic or abdominal aneurysm or current pneumothorax; Painful vaso-occlusive crises; Muscular contractures, Joints' stiffness, or deformities; Neuromuscular problems i.e., myositis or peripheral neuropathy.

ClinicalTrials.gov NCT06529874