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Tests a new ambulance routing plan for stroke patients in rural areas

Compares a new prehospital stroke transport plan with usual care in adults with stroke.

Plain-language title generated from the registry record
Registry title: Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)

Key facts

Where
Camden and Philadelphia, United StatesSee the 2 sites

Where in United States

  • Cooper University HealthCamden, United StatesTaking people
  • 3401 N Broad streetPhiladelphia, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Temple University
Trial code
NCT06530693
Record updated
12 March 2026
Original description
This interventional trial will compare a novel prehospital stroke transport algorithm (OPUS-i) to a traditional prehospital stroke transport algorithm to improve outcomes in rural stroke patients by determining the effect of implementing a data-driven prehospital stroke algorithm on time to and endovascular therapy. The study consists of a multicenter cohort and will last 24 months but individual subject study duration is 90 days.Read full original descriptionShow less

Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)

This interventional trial will compare a novel prehospital stroke transport algorithm (OPUS-i) to a traditional prehospital stroke transport algorithm to improve outcomes in rural stroke patients by determining the effect of implementing a data-driven prehospital stroke algorithm on time to and endovascular therapy. The study consists of a multicenter cohort and will last 24 months but individual subject study duration is 90 days.

Inclusion: Clinical impression of stroke/TIA by EMS clinicians.

Exclusion: Age < 18 years; Prisoner.

ClinicalTrials.gov NCT06530693