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Checking for Early Lung Cancer With Low-Dose CT Scans in Mexico

Tests yearly low-dose CT scans to find lung cancer early in high-risk adults.

Plain-language title generated from the registry record
Registry title: Lung Cancer Screening Program in Mexico

Key facts

Where
Mexico City, MexicoSee the site

Where in Mexico

  • Instituto Nacional de Cancerologia (INCan) MexicoMexico City, MexicoTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Instituto Nacional de Cancerologia de Mexico
Trial code
NCT06535451
Record updated
24 December 2025
Original description
This prospective study aims to detect early-stage lung cancer using low-dose computed tomography (LDCT) in Mexicans aged 50 or older who are current or former heavy smokers, non-smokers exposed to significant wood smoke, or diagnosed with COPD. Annual LDCT, spirometry, and serum biomarker tests will be conducted over 3 years, and a follow-up lasting up to 10 years.Read full original descriptionShow less

Lung Cancer Early Detection With Low-dose Computed Tomography in High-risk Individuals: Experience in Mexico

This prospective study aims to detect early-stage lung cancer using low-dose computed tomography (LDCT) in Mexicans aged 50 or older who are current or former heavy smokers, non-smokers exposed to significant wood smoke, or diagnosed with COPD. Annual LDCT, spirometry, and serum biomarker tests will be conducted over 3 years, and a follow-up lasting up to 10 years.

Inclusion: Eligible participants over fifty years old and one of the next criteria:; Current smokers (>20 pack-years); Former smokers (>20 pack-years) who have quit within the past 15 years,; Non-smokers exposed to wood smoke more than 100 hours/year; Patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD).

Exclusion: History of any type of cancer within the last five years, except non-melanoma skin cancer; Symptoms consistent with some malignant neoplasm; People with a poor physical-emotional condition that reduces their life expectancy or does not ensure adherence to the study; Elimination Criteria; Subjects who cannot be examined by tomography due to physical limitations such as weight; Withdrawal of informed consent.

ClinicalTrials.gov NCT06535451