NCT06540183Completed
Percutaneous Intramyocardial Septal Radiofrequency Ablation for Obstructive Hypertrophic Cardiomyopathy in Children
Percutaneous Intramyocardial Septal Radiofrequency Ablation for Drug-refractory Obstructive Hypertrophic Cardiomyopathy in Children and Adolescents: An Early Feasibility Study
Source: ClinicalTrials.gov · Last updated 15 Jul 2026
Brief summary (registry, in English)
The primary purpose of this study was to demonstrate the safety and efficacy of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA) in children and assessed its performance and functional outcomes in the follow-up. This is a single-arm, single-center study.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 23 (actual)
- First submitted
- 22 Jul 2024
- Start date
- 1 Sept 2020
- Primary completion date
- 1 Nov 2024
- Lead sponsor
- Xijing Hospital
- Diseases
- Hypertrophic cardiomyopathy
- NCT number
- NCT06540183
What you commit to
- Study type: Observational
- Participants enrolled: 23
- From 1 Sept 2020 to the primary completion date, 1 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of concomitant heart disease requiring surgery
Other illness
- Cardiac resynchronization therapy within 3 months
Lab values
- Left ventricular ejection fraction \<40%
Other
- Secondary left ventricular hypertrophy (LVH) related to subaortic stenosis or aortic stenosis
Who the study is looking for
- Clinical diagnosis of hypertrophic obstructive cardiomyopathy
- Age younger than 18 years
- Resting or provoking left ventricular outflow tract gradient ≥ 50 mmHg
- Drug-refractory symptoms or intolerable to pharmaceutical therapies
- Heart function of New York Heart Association ≥ class II
Age in the registry: - to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Xijing hospital Coordinator of this site? Confirm its status | Xi'an | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.