Tests a TENS device for leg movement after stroke
Tests whether electrical stimulation through the skin affects leg movement in adults after stroke.
Plain-language title generated from the registry record
Registry title: Effect of Transcutaneous Electrical Nerve Stimulation on Post-stroke Patients
Key facts
- Where
- Dallas, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT06541015, who can take part
Where in United States
- University of Texas Medical CenterDallas, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Texas Southwestern Medical Center
- Trial code
- NCT06541015
- Record updated
- 30 March 2026
- Original description
The subjects will be asked to attend minimum 15 separate sessions, 6 for testing changes in reflex behaviors, 3 for testing changes in the influence of descending motor tracts on spinal motor neurons, 3 for each testing functional movement in response to a trip event and cross-tilt walking adaptation pattern, as part of their participation in the research study. The estimated amount of time to enroll and collect the data for each of the subjects is four months' time. The data will be analyzed and ready for grant preparation (if successful) in approximately four months after the start of the study.Read full original descriptionShow less
TENS (Transcutaneous Electrical Nerve Stimulation): Effect of Transcutaneous Spinal Direct Current Stimulation on Lower Limb Reflex, Volitional, and Functional Movement Post-stroke
The subjects will be asked to attend minimum 15 separate sessions, 6 for testing changes in reflex behaviors, 3 for testing changes in the influence of descending motor tracts on spinal motor neurons, 3 for each testing functional movement in response to a trip event and cross-tilt walking adaptation pattern, as part of their participation in the research study. The estimated amount of time to enroll and collect the data for each of the subjects is four months' time. The data will be analyzed and ready for grant preparation (if successful) in approximately four months after the start of the study.
Inclusion: History of single unilateral stroke with subsequent lower limb hemiparesis on either side (> 6 months since onset); Ability to walk as part of activities of daily living; Age between 18 and 80; No history of stroke, cerebral palsy, injury or surgery to the lower limb; Currently not taking any central nervous system (CNS) affecting medication; Ability to walk as part of activities of daily living; Age between 18 and 80.
Exclusion: Presence of concurrent severe medical illness including unhealed pressure sore, active or untreated infection, thromboembolic disease, severe contracture, osteoporosis, heterotropic classification, lower limb fracture, severe pulmonary disease or cardiovascular instability, uncontrolled seizure, uncontrolled diabetes; Has received a Botox injection in the lower extremity within the last 4 months; History of prior injury or surgery to the hip or knee; Actively taking medications with agents known to increase (e.g. amphetamines) or decrease motor system excitability; Presence of concurrent severe medical illness including unhealed pressure sore, active or untreated infection, thromboembolic disease, severe contracture, osteoporosis, heterotropic classification, lower limb fracture, severe pulmonary disease or cardiovascular instability, uncontrolled seizure, uncontrolled diabetes; Taking any medication affecting change in CNS; History of prior injury or surgery to the hip or knee; Actively taking medications with agents known to increase (e.g. amphetamines) or decrease motor system excitability; Has received a Botox injection in the lower extremity within the last 4 months; History of any neurological injury other than a single stroke; Presence of significant lower extremity edema - Presence of cardiac pacemaker or any other electrically implanted device - Use of braces limiting harness/Lokomat fit (Any spinal orthoses such as TLSO, HALO); Clinically significant depression, psychiatric disorders, or ongoing drug abuse; History of any neurological injury; Presence of significant lower extremity edema - Presence of cardiac pacemaker or any other electrically implanted device - Use of braces limiting harness/Lokomat fit (Any spinal orthoses such as TLSO, HALO); Clinically significant depression, psychiatric disorders, or ongoing drug abuse; Any cognitive deficit that would prevent informed consent or ability to perform the experiment; Weight greater than 300 pounds; Adults unable to consent, infants, children, teenagers, pregnant women and prisoners will not be included in the study; Suffered a concussion in the last 6 months; Unexplained headaches; Healthy Cohort:; Any cognitive deficit that would prevent informed consent or ability to perform the experiment; Weight greater than 300 pounds; Adults unable to consent, infants, children, teenagers, pregnant women and prisoners will not be included in the study; Suffered a concussion in the last 6 months; Unexplained headaches.
Post Stroke Cohort:.