Follows people with inflammatory brain and spinal cord diseases over time in China
Observes people with multiple sclerosis and related inflammatory nerve diseases to learn outcomes.
Plain-language title generated from the registry record
Registry title: Sun Yat-Sen Cohort of CNS Idiopathic Inflammatory Demyelinating Diseases
Key facts
- Where
- Guangzhou, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18-65 with a central nervous system inflammatory demyelinating disease, such as MS, NMOSD, MOGAD or ADEM. It is an observational study with no extra treatment.
- Age
- 18 to 65 years
- Sex
- All sexes can join.
- Disease stage
- Central nervous system idiopathic inflammatory demyelinating disease: MS, NMOSD, MOGAD, ADEM, clinically isolated syndrome, demyelinating encephalopathy, demyelinating myelitis or brainstem encephalitis.
Main reasons for not taking part
- History of tumors or a central nervous system tumor
- Infection of the central nervous system
- Hereditary, metabolic, toxic, vascular or traumatic demyelinating disease of the brain or spinal cord
- Not keeping to treatment and follow-up
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06541626, who can take part
Where in China
- Sun Yat-sen Memorial HospitalGuangzhou, ChinaContact: Hongxuan WangTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Trial code
- NCT06541626
- Record updated
- 7 August 2024
- Original description
The goal of this observational study is to learn about pathogenesis and clinical prognosis of CNS IIDD in the Chinese population and to provide evidence-based clues for clinical treatment decisions.Read full original descriptionShow less
Sun Yat-Sen Prospective Cohort Study of Central Nervous System Idiopathic Inflammatory Demyelinating Diseases
The goal of this observational study is to learn about pathogenesis and clinical prognosis of CNS IIDD in the Chinese population and to provide evidence-based clues for clinical treatment decisions.
The main questions it aims to answer are:
Question 1: Clarify the clinical characteristics and prognostic factors of various diseases (MS, NMOSD, MOGAD, etc.) within IIDD in the Chinese population.
Question 2: Analyze the relationship between biomarkers and the occurrence, progression, and prognosis of CNS IIDD cases in our hospital.
Participants will
1. Receive the recommended diagnosis and treatment plans from current international and national guidelines or expert consensus, without additional special interventions. 2. Receive clinical evaluation, follow-up, and management from dedicated neuroimmunology specialists.
Inclusion: Patients aged 18-65 years with central nervous system idiopathic inflammatory demyelinating diseases (CNS IIDD); The clinical syndrome of the attack meets one of the following: MS, NMOSD, MOGAD, ADEM, clinically isolated syndrome, demyelinating encephalopathy, demyelinating myelitis, or brainstem encephalitis (see below A-E); Agree to participate in this study and sign the informed consent form.
Exclusion: History of tumors or diagnosis of central nervous system tumors; Hereditary, metabolic, toxic, vascular, or traumatic demyelinating diseases of the brain/spinal cord; Infectious lesions of the central nervous system; Non-compliance with treatment and follow-up.