Wearable headband tracks sleep and seizure risk in intractable epilepsy
Tests a wearable headband in adults with hard-to-control epilepsy.
Plain-language title generated from the registry record
Registry title: Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs
Key facts
- Where
- Durham, United StatesSee the site
Where in United States
- Duke University Health SystemDurham, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Duke University
- Trial code
- NCT06545643
- Record updated
- 19 October 2026
- Original description
Epilepsy, a prevalent neurological disorder, affects 40% of patients with uncontrolled seizures despite medications. Sleep disturbance exacerbates epilepsy, and vice versa, but existing literature suffers from limitations. Studies conducted in hospital settings provide only brief observation periods and fail to capture the natural sleep environment. Wearable technology offers a promising solution, providing a nuanced understanding of the relationship between seizures and sleep. The Dreem headband, an EEG-based wearable, is well-suited for such studies, offering ease of use and validated accuracy. This technology enables extended observation periods under stable medication conditions, essential for assessing the complex interplay between sleep and epilepsy. By elucidating the impact of sleep on seizures, the researchers seek to identify patient populations where sleep significantly influences seizure susceptibility, ultimately informing personalized epilepsy treatments.Read full original descriptionShow less
Personalized Risk Assessment of Seizures Sensitive to Poor Sleep: a Longitudinal Study Using Wearable Electroencephalography Devices
Epilepsy, a prevalent neurological disorder, affects 40% of patients with uncontrolled seizures despite medications. Sleep disturbance exacerbates epilepsy, and vice versa, but existing literature suffers from limitations. Studies conducted in hospital settings provide only brief observation periods and fail to capture the natural sleep environment. Wearable technology offers a promising solution, providing a nuanced understanding of the relationship between seizures and sleep. The Dreem headband, an EEG-based wearable, is well-suited for such studies, offering ease of use and validated accuracy. This technology enables extended observation periods under stable medication conditions, essential for assessing the complex interplay between sleep and epilepsy. By elucidating the impact of sleep on seizures, the researchers seek to identify patient populations where sleep significantly influences seizure susceptibility, ultimately informing personalized epilepsy treatments.
Inclusion: Age > 18 years; At least 2 seizures per week based on clinical notes; Patients where medications will stay stable over the study period; 40% of both spikes and spindles are identifiable on the dreem headband based on the screening night.
Exclusion: Cognitive impairment; Psychiatric comorbidities which may influence sleep; No bedpartner/caregiver to observe seizures; Low agreement (below 60%) between Dreem's sleep scoring and manual scoring will be excluded from the study; Apnea-hypopnea index of > 10/h.