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Tests a dietary intervention in adults with atopic dermatitis and allergic diseases

Tests a diet change in adults with atopic dermatitis and related allergic conditions.

Plain-language title generated from the registry record
Registry title: Dietary Intervention on Atopy

Key facts

Where
Singapore, SingaporeSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 21 and 65 years old?

Source: NCT06547372, who can take part

Where in Singapore

  • National University of SingaporeSingapore, SingaporeTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
National University of Singapore
Trial code
NCT06547372
Record updated
1 April 2026
Original description
Diet is a key determinant of overall health, with growing evidence associating dietary patterns with allergic diseases. Among these, atopic dermatitis (AD) is of particular interest as it often represents the earliest manifestation of the atopic triad. Investigating dietary interventions in AD therefore provides a relevant model to better understand how diet may influence the onset and progression of allergic disease more broadly.Read full original descriptionShow less

Dietary Intervention on Atopy

Diet is a key determinant of overall health, with growing evidence associating dietary patterns with allergic diseases. Among these, atopic dermatitis (AD) is of particular interest as it often represents the earliest manifestation of the atopic triad. Investigating dietary interventions in AD therefore provides a relevant model to better understand how diet may influence the onset and progression of allergic disease more broadly.

Inclusion: Presence of current, mild-to-moderate atopic dermatitis/eczema at flexural areas; 21 to 65 years of age (inclusive) at screening; Must be English-literate and able to give informed consent in English; Be residing in Singapore and will not be travelling outside of Singapore during the study period; Reliable and willing to follow study procedures and be available for the duration of the study; Non-smokers (tobacco and e-cigarette); Non-drinker (no regular or frequent consumption of alcohol); Overtly healthy with no pre-existing medical conditions (e.g., diabetes, hypertension, cancer, blood disorders, degenerative/liver/autoimmune/immune/renal diseases, or psychiatric conditions); No food allergies to test foods; No needle phobia; Be willing to follow the instruction provided by the investigators on the use of any moisturiser, cosmetics, and/or topical cream on the skin throughout the entire duration of the study.

Exclusion: Concurrent participation in other research studies; Regular use of strong medication (western and/or traditional), therapies, and alternative medications; Regular nutritional supplements in the past 12 months Regular consumption of oral contraceptive pills and/or steroid hormones; Any long-term hospitalisation or surgery during the 6 months before enrolment in study; Known or ongoing psychiatric disorders within 3 years; History of bleeding diathesis or coagulopathy (or any bleeding disorders); Pregnancy or lactating individuals; Known severe nutritional deficiency; Vegetarian/vegans (as meat will be included in the diet); Individuals who made a significant dietary change in the past 12 months; Having a pre-existing dietary restriction that would interfere with the adherence to a whole diet meal; Antibiotic use in the past 2 months; Significant change in weight (+/- 5.0%) during the past month; Having donated blood of more than 500 mL within 4 weeks of study enrolment.

ClinicalTrials.gov NCT06547372