NCT06562036Completed
Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in Children
Efficacy of Milrinone Plus Sildenafil in the Treatment of Neonates With Persistent Pulmonary Hypertension: A Single-Center, Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 26 Aug 2024
Brief summary (registry, in English)
Neonates with persistent pulmonary hypertension (PPH) should be administered inhaled nitric oxide (iNO) and extracorporeal membrane oxygenation (ECMO), but these are not available in most resource-constrained settings like ours. This study was planned to compare the outcomes of Milrinone plus Sildenafil versus Sildenafil alone in the treatment of PPH in neonates.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 42 (actual)
- First submitted
- 17 Aug 2024
- Start date
- 1 Dec 2023
- Primary completion date
- 31 May 2024
- Lead sponsor
- Muhammad Aamir Latif
- NCT number
- NCT06562036
What you commit to
- Study type: Interventional
- Participants enrolled: 42
- From 1 Dec 2023 to the primary completion date, 31 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Neonates having congenital heart defects (CHDs)
- History of any surgical intervention
Other
- Congenital diaphragmatic hernia
- Lung anomalies
Who the study is looking for
- Patients of either gender
- Aged between 1-28 days
- Birth weight above 2000 grams
- Diagnosed with persistent pulmonary hypertension (as per echocardiography)
Age in the registry: 1 day to 28 days · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital and institute of Child Health Coordinator of this site? Confirm its status | Multan | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.