Comparative Assessment of Sleep Positive Airway Pressure Modalities (CASPAM)
Key facts
- Who runs it
- National University of Malaysia
- Where
- Cheras, MalaysiaSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 50 people, planned
- Started
- 1 Sept 2024
- Expected to end
- 1 Jan 2027
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- CPAP Airsense 10 vs Air-Mini
- Record updated
- 14 July 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Aged ≥ 18 years
- Patients diagnosed with moderate to severe OSA (based on AHI classification from sleep study performed)
- Patients who are able to understand and answer the questionnaire given
Who cannot take part
- Patients who had underlying Obesity Hypoventilation Syndrome (OHS)
- Patients who had underlying co-morbidities that worsen apnea symptoms, such as congestive cardiac failure, active malignancy, narcolepsy, active alcohol or drug abuse, treatment-refractory dementia, psychotic illness and active use of drugs that disturb the sleep architecture (i.e hypnotics or stimulants of central nervous system)
- Patients who are unable to give consent to the study
- Patients who have been diagnosed with OSA and already on CPAP machine
Where in Malaysia
- National University of Malaysia, Faculty of MedicineCheras, MalaysiaContact: Mohamed Faisal Abdul HamidTaking people
About the trial
What the trial wants to find out
Obstructive sleep apnea (OSA) has been one of the topmost global health problems. It is an underdiagnosed disease which have a huge burden on healthcare if left untreated. Almost 80-90% of adults are underdiagnosed of OSA Obesity primarily is one of the supreme risk factors for developing OSA. Globally, obesity cases have risen affecting almost two billion people. According to National Health and Morbidity Survey (NHMS) 2019, 1 in 2 adults in Malaysia were overweight or obese. Report from World Obesity Atlas 2023 predicts that adult obesity will rise 4.7% annually from 2020 - 2035, while child obesity will increase by 5.3% per year over similar timeline. Overweight individuals will have a significant economic impact on Malaysia's Gross Domestic Product (GDP) by 2035 by 2.8% which is estimated to be about RM 3.2 trillion.
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Sequalae of OSA is divided into two (cardiovascular-metabolic effect and neurocognitive effect). This group of patients are at high risk of developing hypertension, insulin resistance, dyslipidemia which then leads to pulmonary hypertension and heart failure. More importantly, from the neurocognitive point of view, persistent sleep deprivation will lead to poor concentration, impaired memory, personality changes affecting overall self-performance which can lead to depression and compromising safety as they have higher risk of work-related accidents.
The 2 groups in the trial
- CPAP Airsense 10Existing treatment, for comparison
Participants in CPAP Airsense 10
Treatment: CPAP Airsense 10 vs Air-Mini
- CPAP AIr-MiniExisting treatment, for comparison
Participants in CPAP AIr-Mini
Treatment: CPAP Airsense 10 vs Air-Mini
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Comparative Assessment of Sleep Positive Airway Pressure Modalities (CASPAM) Trial: Conventional CPAP (AirSense 10) Versus Portable CPAP (AirMini) in Patients With Obstructive Sleep Apnea-A Randomized Crossover Study of User Preference
- Record updated
- 14 July 2026