Studies sleep disorders in people with Parkinson disease and REM sleep behavior disorder
Tests sleep recordings in adults with Parkinson disease or isolated REM sleep behavior disorder.
Plain-language title generated from the registry record
Registry title: Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease
Key facts
- Where
- Clermont-Ferrand, Lille, Lyon, Nantes, Nîmes, and Paris, FranceSee the 6 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with Parkinson's disease, adults with isolated REM sleep behavior disorder, and healthy adults without brain or mental illness.
- Age
- 18 years or older (the record says "superior 18 years").
- Sex
- All sexes can join.
- Disease stage
- Parkinson's disease diagnosed by MDS criteria, with a MoCA score greater than 20/30. Or REM sleep behavior disorder confirmed by a sleep test (polysomnography), with no Parkinson's disease, multiple system atrophy or Lewy body dementia.
- Earlier treatment
- People with Parkinson's disease cannot have treatment with deep brain stimulation.
- Biomarker or test result
- REM sleep behavior disorder must be shown on polysomnography: more than 18% of REM sleep without chin atonia, and/or REM sleep behaviors on video-polysomnography.
Main reasons for not taking part
- Pregnant or breastfeeding women
- People under guardianship or conservatorship
- People deprived of liberty
- People with Parkinson's disease treated with deep brain stimulation
- Healthy controls with a neurological or psychiatric disease
Read by machine on 12 November 2026.
Where in France
- CHU de Clermont-FerrandClermont-Ferrand, FranceContact: Maria-Livia FANTINI, MDTaking people
- CHU de LilleLille, FranceContact: Lise LANVIN, MDTaking people
- CHU de LyonLyon, FranceContact: Laure PETER-DEREX, MDTaking people
- CHU de NantesNantes, FranceContact: Laurène LECLAIR-VISONNEAU, MDTaking people
- CHU de NîmesNîmes, FranceContact: Beatriz ABRIL, MDTaking people
- CHU Pitie SalpetriereParis, FranceContact: Pauline DODET, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Assistance Publique - Hôpitaux de Paris
- Trial code
- NCT06582121
- Record updated
- 6 March 2026
- Original description
Multicenter controlled study of sleep disorders in isolated REM Behavior Disorder and Parkinson\'s disease (SOMPARK)Read full original descriptionShow less
Controlled, Multicenter Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease
Multicenter controlled study of sleep disorders in isolated REM Behavior Disorder and Parkinson\'s disease (SOMPARK)
Inclusion: Common to all groups:; Age superior 18 years; Patients who have received complete information about the study from an investigator and who fully consent to participate; For Parkinson Disease (PD):; Patients followed for PD diagnosed according to international criteria for the diagnosis of PD (MDS criteria),; A MoCA score greater than 20/30; No treatment with deep brain stimulation; For REM Sleep Behavior Disorder (RBD):; Diagnosis of RBD according to ICSD-3 criteria: presence on polysomnography of an abnormal elevation of muscle tone during REM sleep (more than 18% of REM sleep without chin atonia) and/or the presence of REM sleep behaviors on video-polysomnography,; Absence of progressive neurodegenerative pathology: absence of diagnostic criteria for PD, multiple system atrophy, or Lewy body dementia; For healthy controls:; No neurological or psychiatric disease.
Exclusion: Common to all groups:; Pregnant or breastfeeding women; Subjects under guardianship/conservatorship; Persons deprived of liberty.