Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis
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- Who runs it
- University of Salerno
- Trial code
- NCT06589063
- Record updated
- 7 April 2026
- Original description
LOW-TAVR is a real-world, retrospective and prospective, multicenter Italian registry aimed at evaluating the characteristics and clinical outcomes of patients with severe low flow, low gradient aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) and, in particular:Read full original descriptionShow less
Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis: the Multicenter LOW-TAVR Registry
LOW-TAVR is a real-world, retrospective and prospective, multicenter Italian registry aimed at evaluating the characteristics and clinical outcomes of patients with severe low flow, low gradient aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) and, in particular:
* risk factors * gender differences * comorbidities * pharmacological treatment * TAVR procedural characteristics * periprocedural and in-hospital complications * clinical outcome at 30-day, 1-year, 2-year and 5-year follow-up
Inclusion: LFLG-AS diagnosis according to current European Society of Cardiology guidelines; Age 18 years or older; Written informed consent.
Exclusion: LFLG-AS referred for medical treatment or undergoing surgery; LFLG-AS pseudo-severe or non-confirmed severe aortic stenosis.