Eating Disorders Genetics Initiative 2
Key facts
- Who runs it
- University of North Carolina, Chapel Hill
- Where
- Chapel Hill, United StatesSee the siteAlso in 4 other countries, 4 sites
- Trial code
- Status
- Recruiting
- People taking part
- 20,000 people, planned
- Started
- 28 Oct 2024
- Expected to end
- 1 Sept 2027
- Type of study
- Observational, 5 groups
- Treatments tested
- Eating disorder diagnosis group
- Record updated
- 8 July 2026
Who can take part
- Age
- 12 years to 99 years
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 3 criteriaShow less
Who can take part
- A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms
- Age 12-99 years, depending on country. (US enrollment age is 18-99)
Who cannot take part
- History of subthreshold disordered eating behaviors
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 12 and 99 years old?
Where in United States
Also in 4 other countries, 4 sites
- University of North Carolina at Chapel HillChapel Hill, United StatesContact: Laura M Thornton, PhDTaking people
About the trial
What the trial wants to find out
The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.
The 5 groups in the trial
- Anorexia nervosa
Individuals with a self-reported lifetime history of anorexia nervosa.
Treatment: Eating disorder diagnosis group
- Bulimia nervosa
Individuals with a self-reported lifetime history of bulimia nervosa.
Treatment: Eating disorder diagnosis group
- Binge-eating disorder
Individuals with a self-reported lifetime history of binge-eating disorder.
Treatment: Eating disorder diagnosis group
- ARFID
Individuals with a self-reported lifetime history of avoidant restrictive food intake disorder.
Treatment: Eating disorder diagnosis group
- Control
Individuals with no history of disordered eating behaviors or symptoms
Treatment: Eating disorder diagnosis group
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Fit questions
- Built from NCT06594913, who can take part
- Record updated
- 8 July 2026