NCT06596746Recruiting
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
Neurodegenerative Diseases Progression Markers (MARKERS-NDD): a Real-world Data Longitudinal Prospective Study
Source: ClinicalTrials.gov · Last updated 2 Sept 2026
Brief summary (registry, in English)
MARKERS-NDD is a prospective, observational, longitudinal study, which aims to collect data from patients affected by neurodegenerative diseases (NDD) followed longitudinally for routine examinations performed as part of normal clinical practice. Data collected from clinical evaluations, movement analysis, brain imaging, neuropsychological and electroencephalographic assessments, blood chemistry tests will be analysed to carry out statistical investigations and predictive analyses, also using artificial intelligence systems, which allow the identification of new early markers of diagnosis and prognosis of neurodegenerative diseases.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 9 Aug 2024
- Start date
- 9 Sept 2024
- Primary completion date
- 9 Sept 2034
- Lead sponsor
- Casa di Cura San Raffaele Cassino
- Diseases
- ALS (motor neurone disease), Frontotemporal dementia, Lewy body dementia, Alzheimer disease, Parkinson disease
- NCT number
- NCT06596746
What you commit to
- Study type: Observational
- Planned participants: 600
- From 9 Sept 2024 to the primary completion date, 9 Sept 2034
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- There are no restrictions for participation in the study based on age, severity of illness or presence of cognitive impairment, as long as the person is able to complete the research assessments.
Who the study is looking for
- Patients with diagnosis of Parkinson's Disease, Parkinsonism and Movement Disorders
- Patients with diagnosis of Parkinson's Disease
- Diagnosis of Parkinson's Disease according to the United Kingdom (UK) Parkinson's Disease Society Brain Bank
- Diagnosis of Movement Disorder not related to Parkinson's Disease
- Diagnosis of Multiple System Atrophy (MSA) in accordance with Second Consensus Statement on Diagnosis of Multiple System Atrophy;
- Diagnosis of Progressive Supranuclear Palsy according to Movement Disorder Society for Diagnosis of Progressive Supranuclear Palsy;
- Diagnosis of Essential Tremor
- Willing to participate in the study, understand the procedures and sign the informed consent.
- Patients affected by cognitive impairment (CI) and dementia
- Diagnosis of probable:
- Lewy Body Dementia
- Alzheimer's Disease
- Mild Cognitive Decline
- Subjective memory complaints
- Willing to participate in the study, understand the procedures and sign the informed consent.
Age in the registry: 10 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| San Raffaele Cassino Coordinator of this site? Confirm its status | Cassino | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.