Checks the heart in people hospitalized for COPD flare-ups
Studies whether COPD flare-ups cause temporary heart weakening in adults hospitalized for them.
Plain-language title generated from the registry record
Registry title: Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital
Key facts
- Where
- Gothenburg, SwedenSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults in hospital because their chronic obstructive pulmonary disease (COPD) has suddenly got worse. It studies whether this causes temporary heart muscle stunning (Takotsubo).
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Admitted to a hospital ward for a sudden worsening (exacerbation) of COPD, and joining within 72 hours of admission.
Main reasons for not taking part
- Earlier heart attack
- Known lasting problem with how part of the heart wall moves, or weak heart pumping (LVEF below 50%)
- Expected to be unable to follow the trial steps, for example because of dementia
Read by machine on 9 November 2026.
Where in Sweden
- Department of Emergency Medicine and Geriatrics, Sahlgrenska University Hospital/SGothenburg, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sahlgrenska University Hospital
- Trial code
- NCT06597331
- Record updated
- 17 September 2026
- Original description
The goal of this prospective observational study is to investigate to what extent acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) triggers Takotsubo-stunning, and how this affects the outcome for these patients.Read full original descriptionShow less
Prospective Observational Study of Myocardial Stunning in Patients Hospitalized for Exacerbation of Chronic Obstructive Pulmonary Disease
The goal of this prospective observational study is to investigate to what extent acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) triggers Takotsubo-stunning, and how this affects the outcome for these patients.
The main questions it aims to answer are:
1. What is cumulative incidence of Takotsubo-stunning in patients hospitalized for AE-COPD at Sahlgrenska University Hospital/S (Gothenburg, Sweden)? 2. Among patients hospitalized for AE-COPD at Sahlgrenska University Hospital/S, what is the risk of in-hospital clinical manifestations of acute heart failure in patients with Takotsubo-stunning compared to those without?
Inclusion: Adult patients (≥ 18 years old) admitted to hospital ward for AE-COPD; Inclusion within 72 hours of admission,; Written informed consent.
Exclusion: Expected inability to comply with the protocol (e.g. dementia); Prior acute myocardial infarction or known pre-existing persistent regional wall motion abnormality or left ventricular dysfunction (left ventricular ejection fraction [LVEF] <50%).