Brain Imaging During Shoulder Movement After Stroke
Uses brain and spinal scans during shoulder movement in adults with chronic stroke weakness.
Plain-language title generated from the registry record
Registry title: Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke
Key facts
- Where
- Chicago, United StatesSee the site
Where in United States
- Northwestern UniversityChicago, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Northwestern University
- Trial code
- NCT06598150
- Record updated
- 1 October 2025
- Original description
This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.Read full original descriptionShow less
Mapping Corticoreticulospinal Motor Control Using Brainstem and Spinal Cord fMRI in Chronic Hemiparetic Stroke
This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.
Inclusion: Adults aged at least 18y; Able to perform shoulder abduction task (confirmed during screening and initial examination); Safe to undergo MRI; Able to follow visual instructions using MRI-compatible vision correction goggles; No brainstem or cerebellar lesions; No severe concurrent medical problems; Cognitive/attentional capacity to focus on a task; Able to communicate in English or Spanish; Additional inclusion criteria for stroke participants:; Have sustained only one unilateral subcortical, ischemic lesion in the territory supplied by the Middle Cerebral Artery (confirmed by clinical or radiological reports) at least one year prior to participation in this project; Paresis confined to one side, with moderate-to-severe motor impairment of the upper limb (Upper Extremity Fugl-Meyer score between 10 and 45).
Exclusion: brain radiation; Concurrent enrollment in an intervention study; Concurrent use of medications known to suppress central nervous system activity; Diagnosis/history of:; dementia; Parkinson's disease; MRI contraindications; Severe claustrophobia; Pregnant women; Prisoners; Vulnerable populations; multiple sclerosis; brain tumor; traumatic brain injury.