Comparing Two Staple Line Types in Lung Cancer Lobe Removal Surgery
Tests reinforced versus standard staple lines in adults having lung cancer lobe removal.
Plain-language title generated from the registry record
Registry title: Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
Key facts
- Where
- Surrey, CanadaSee the site
- Phase
- Phase 1
Where in Canada
- Surrey Thoracic Surgery GroupSurrey, CanadaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Surrey Thoracic Surgery Group
- Trial code
- NCT06602661
- Record updated
- 19 September 2024
- Original description
Prolonged Air Leak (PAL) is a common and serious problem after lung surgery. It can lead to worse patient outcomes, longer hospital stays, and higher costs. Reinforced staplers are designed to make the staple line stronger and reduce the risk of PAL. However, investigators don't know if they are better than standard staplers, especially in a specific type of lung surgery called fissureless lobectomy for lung cancer. This study aims to find out if reinforced staplers are more effective at reducing PAL and its complications compared to non-reinforced staplers.Read full original descriptionShow less
A Prospective Randomized Study of Reinforced Vs Non-reinforced Staple Lines in Fissureless Lobectomy
Prolonged Air Leak (PAL) is a common and serious problem after lung surgery. It can lead to worse patient outcomes, longer hospital stays, and higher costs. Reinforced staplers are designed to make the staple line stronger and reduce the risk of PAL. However, investigators don't know if they are better than standard staplers, especially in a specific type of lung surgery called fissureless lobectomy for lung cancer. This study aims to find out if reinforced staplers are more effective at reducing PAL and its complications compared to non-reinforced staplers.
Reinforced staplers have been used in lung surgeries and have shown to reduce PAL. For example, staplers with special materials like polyglycolic acid (PGA) sheets have shown lower air leakage and fewer days with chest tubes. Other materials like expanded polytetrafluoroethylene (ePTFE) sleeves have also been used to manage air leaks in different types of lung surgeries. However, their effectiveness in fissureless lobectomy has not been studied yet.
Inclusion: Patients aged 18 and over; Patients undergoing fissureless lobectomy for lung carcinoma.
Exclusion: Patients with previous lung resection on the same side; Patients undergoing lobectomy for indications other than lung cancer; Patients with a history of pleural adhesions; Patients suitable for sub lobar resections.