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Immune Cell Markers in Cystic Fibrosis Patients With Mycobacterial Lung Infection

Studies immune cell responses in adults with cystic fibrosis and non-tuberculous mycobacterial lung infection.

Plain-language title generated from the registry record
Registry title: Cellular Markers in Treated or Untreated Non-tuberculous Mycobacterial Respiratory Infection in Patients With Cystic Fibrosis

Key facts

Where
Montpellier, FranceSee the site

Where in France

  • CHU de Montpellier - Hôpital Arnaud de VilleneuveMontpellier, FranceTaking people

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Trial details

Who runs it
University Hospital, Montpellier
Trial code
NCT06602869
Record updated
10 July 2025
Original description
This study evaluates a diagnostic serological test for Non-Tuberculous Mycobacteria (NTM) infection in cystic fibrosis patients by measuring T cell response. It aims to highlight a dynamic response associated to the pathogen's presence. This multicenter case-control study involves two populations, providing a better understanding of the circulating T-IFNγ-MNT response in these patients.Read full original descriptionShow less

Cellular Markers During a Non-tuberculous Mycobacterial Respiratory Infection, Treated or Untreated, in Patients With Cystic Fibrosis

This study evaluates a diagnostic serological test for Non-Tuberculous Mycobacteria (NTM) infection in cystic fibrosis patients by measuring T cell response. It aims to highlight a dynamic response associated to the pathogen's presence. This multicenter case-control study involves two populations, providing a better understanding of the circulating T-IFNγ-MNT response in these patients.

Inclusion: Patient ≥18 years; Patient previously included in the CIMeNT study; Patient with a confirmed diagnosis of cystic fibrosis regardless of CFTR genotype; Patient affiliated to the social security system; Patient registered in the French Cystic Fibrosis Registry; Adult patient capable of spontaneous expectoration or after induction.

Exclusion: Lung transplant patients; Person placed under judicial protection; Pregnant and breastfeeding women.

ClinicalTrials.gov NCT06602869