Checking Joint Movement Problems in People With Stroke or Mini-Stroke
Tests a standard hands-on joint exam in adults with stroke or mini-stroke.
Plain-language title generated from the registry record
Registry title: Somatic Dysfunction in Patients With Acute Cerebrovascular Disease
Key facts
- Where
- Sacramento, United StatesSee the site
Where in United States
- University of California, Davis Medical CenterSacramento, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of California, Davis
- Trial code
- NCT06605014
- Record updated
- 26 September 2025
- Original description
The goals of this observational study are to test the reliability of a new, standardized physical examination method to identify motion problems within joints or groups of joints among adult asymptomatic volunteers and in patients hospitalized with stroke or stroke-like episodes (e.g., transient ischemic attack, TIA). The main questions this investigation aims to answer are:Read full original descriptionShow less
Characterization of Somatic Dysfunction in Patients With Acute Cerebrovascular Disease
The goals of this observational study are to test the reliability of a new, standardized physical examination method to identify motion problems within joints or groups of joints among adult asymptomatic volunteers and in patients hospitalized with stroke or stroke-like episodes (e.g., transient ischemic attack, TIA). The main questions this investigation aims to answer are:
* Can different, independent providers reliability quantify motion pattern problems using a systematic approach called, The Functional Pathology of the Musculoskeletal System (FPMSS) model? * Are there differences in joint(s) motion patterns among asymptomatic volunteers, patients with TIA (people with brain disease without new neurologic disability), and recent ischemic stroke (patients with new stroke-related-disability, e.g., paralysis)? * Is there an association between joint(s) motion impairment severity and stroke survivor outcomes?
Participants (asymptomatic and those with stroke) will undergo a set of repeated paired, musculoskeletal physical exams by independent providers blinded to each other's assessments and patient information. Researchers will compare the severity, location, and quantity of joint(s) motion impairment between these three groups with the physical examination methodology (FPMSS). Clinical information (e.g., test results, diagnoses, brain imaging, medical history) will be collected from patients admitted for TIA and stroke. Enrolled participants with recent stroke will complete a survey three months after hospitalization to determine their self-perceived quality-of-life.
Inclusion: adults ≥18 years; Admission diagnosis:; ischemic stroke OR; transient ischemic attack (TIA). A prior history of TIA but without stroke may be enrolled; Neurologic stability or lack of significant deterioration (i.e. ∆ NIHSS<4) for at least 24 hours (defined by clinical documentation and/or communication with provider team(s)) in stroke subjects; Able to sit upright, lie supine, and when able lateral recumbent left/right positions with assist independently or with minimal person assist; Anticipated length of stay greater > or = 2 days for ischemic stroke. TIA patients average length of stay is < 2 days, and can be enrolled in the study.
Exclusion: Prior history of ICH, ischemic stroke, confirmed by imaging and/or clinical evaluation. Patients with imaging showing "chronic stroke" who have never received a diagnosis of stroke and/or have not been previously symptomatic may still be enrolled, based on the Investigator's clinical judgement; Acute skeletal fracture or known dislocation; history of pathologic (osteoporotic or neoplastic) skeletal fracture of thoracic cage, hip/pelvis/sacrum, or vertebral column; History of spinal cord injury with residual neuromuscular or sensory disability; History of recent trauma within the past 30 days; Clinical condition that would interfere with execution of movement or palpatory diagnostic testing, e.g. chronic pain; History of spinal surgery; Spinal column support brace (e.g. cervical collar); Anticipated neurosurgical intervention during hospitalization: decompressive hemicraniectomy, hematoma evacuation (defined by clinical documentation and/or communication with provider team(s)); Current endotracheal intubation (*note: extubated patients can be evaluated for eligibility); Known ligament, musculotendinous, or bone lesion.