Fact CheckerSign in

NCT06605326CompletedPhase 4

Subcutaneous Treprostinil as a Bridge to Lung Transplantation in Severe Pulmonary Hypertension: A Single-Arm Retrospective Study

Source: ClinicalTrials.gov · Last updated 23 Sept 2024

Brief summary (registry, in English)

This single-arm, retrospective study aims to evaluate the safety and efficacy of subcutaneous treprostinil as a bridge therapy for lung transplantation in patients with severe pulmonary hypertension (PH). A total of 46 patients with either pulmonary arterial hypertension (PAH) or chronic lung disease-associated PH (CLD-PH) were included, all of whom were referred for lung transplantation between January 1, 2015, and September 1, 2024. The study examines changes in clinical, functional, and hemodynamic parameters following 3-6 months of treprostinil therapy.

Status (registry)
Completed
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
46 (actual)
First submitted
18 Sept 2024
Start date
1 Jan 2015
Primary completion date
1 Sept 2024
Lead sponsor
Guangzhou Institute of Respiratory Disease
NCT number
NCT06605326

What you commit to

  • Study type: Interventional · Phase 4
  • Participants enrolled: 46
  • From 1 Jan 2015 to the primary completion date, 1 Sept 2024
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Patients with PH caused by left heart disease
  • Patients unable to undergo lung transplantation due to medical conditions
  • Patients with a history of severe drug allergies

Who the study is looking for

  • Patients diagnosed with severe pulmonary hypertension (PAH or CLD-PH) requiring lung transplantation
  • Age 18 years or older
  • Able to provide informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.