Tests CoQ10 and glutathione to prevent kidney injury after heart surgery
Tests two supplements against placebo in adults having heart bypass surgery.
Plain-language title generated from the registry record
Registry title: Prevent Cardiac Surgery Associated AKI Trial
Key facts
- Where
- Washington D.C., United StatesSee the site
- Phase
- Phase 2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT06620523, who can take part
Where in United States
- George Washington University HospitalWashington D.C., United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- George Washington University
- Trial code
- NCT06620523
- Record updated
- 14 October 2026
- Original description
Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily 1200 mg of Co enzyme Q10 (CoQ10) and 1000 mg of Glutathione (GSH), the first dose will be given the day before surgery and continues while admitted up to 1 week. Blood and urine samples will be collected. Adverse events related to the study drugs will be collected.Read full original descriptionShow less
Efficacy of Mitochondrial Directed Therapy in Prevention of Cardiac Surgery Associated AKI Prevent Cardiac Surgery Associated AKI Trial (Prevent CSA-AKI Trial)
Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily 1200 mg of Co enzyme Q10 (CoQ10) and 1000 mg of Glutathione (GSH), the first dose will be given the day before surgery and continues while admitted up to 1 week. Blood and urine samples will be collected. Adverse events related to the study drugs will be collected.
Inclusion: Adult 18-70 years of age; Undergoing elective CPB (Cardiopulmonary Bypass) surgery; Baseline GFR (Glomerular Filtration Rate) ≥45 ml/min.
Exclusion: Status post-kidney transplant; Allergy to CoQ10; Allergy to Glutathione; Allergy to Cellulose; GFR (Glomerular Filtration Rate) <45 ml/min; Solitary kidney; Pregnant women.