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TerminatedPhase 1

tDCS and Cognitive Training for Restrictive Eating Disorders

Key facts

Who runs it
University of Minnesota
Where
Minneapolis, United StatesSee the site
Trial code
Status
Terminated
Phase
Phase 1
People taking part
1 person enrolled
Started
2 Aug 2024
Ended
20 May 2026
Type of study
Interventional, 2 groupsOne group gets a sham (pretend) treatment, for comparison.
Treatments tested
  • Active tDCS sessions, StarStim device
  • Sham (fake) tDCS sessions
Record updated
22 October 2026
Why it stopped
Slow accrual/low enrollment

Who can take part

Age
18 years to 65 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 12 criteriaShow less

Who can take part

  • Age 18-65 years
  • Self-reported enrollment in outpatient-level treatment at local eating disorder treatment centers in the Twin Cities region, and meeting DSM-5 criteria for AN (mild severity, based on BMI greater than or equal to 17.0 kg/m2) or atypical AN diagnosis (based on MINI and EDE assessments)
  • Participant must be capable of giving informed consent, based on UCSD Brief Assessment of Capacity to Consent (UBACC) risk assessment
  • Sufficient spoken English so as to be able to comprehend testing procedures. Normative ranges on a C-RENAL blood panel (panel and ranges specified here: https://labguide.fairview.org/showtest.asp?testid=3321)

Who cannot take part

  • Neurological condition or other developmental disorder
  • Serious psychiatric disorder known to affect brain functioning and cognitive performance (e.g., schizophrenia, schizoaffective disorder)
  • Medical instability, which will be evident based on required outpatient treatment status. In standard eating disorders treatment, individuals who are not medically stable are referred to higher levels of care (e.g., residential treatment, inpatient). Therefore, if a participant is enrolled in higher level care for their eating disorder diagnosis, this indicates medical instability and they will be excluded from enrollment in this study
  • tDCS contraindication (e.g., history of craniotomy, history of metallic cranial plates, screws, implanted devices)
  • Substance abuse in the participant
  • Acute suicidality (suicidalideation with a plan or intent), assessed via MINI suicidality module and Beck Depression Inventory suicide item
  • Acute homicidality (homicidal ideation with a plan or intent), assessed via MINI
  • Moderate, severe or extreme AN diagnostic severity, based on BMI as per DSM-5 criteria (e.g., BMI <17.0 kg/m2)

Where in United States

  • University of MinnesotaMinneapolis, United States

About the trial

What the trial wants to find out

This study looks at adults with restrictive eating disorders who are currently receiving outpatient treatment for their eating disorder to examine whether a new brain stimulation technique called non-invasive transcranial direct current stimulation (tDCS) can enhance brain training. Participation involves interviews, assessments, 10 sessions of brain stimulation (active or sham), and computerized brain training over a 3-4 week period, with one post-intervention visit, and one 1-month follow-up visit.

The 2 groups in the trial

  • Active tDCSTreatment being tested

    10 Active tDCS sessions: 10 active sessions of transcranial direct current stimulation paired with cognitive training tasks. Device used is StarStim.

    Treatment: Active tDCS sessions, StarStim device

  • Sham (fake) tDCSSham treatment, for comparison

    10 Sham (fake) tDCS sessions: 10 fake sessions of transcranial direct current stimulation paired with cognitive training tasks. The device will be on the participants head, but the current will not be active.

    Treatment: Sham (fake) tDCS sessions

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
22 October 2026