Frontlight ResearchEarly access
Taking people in United StatesPhase 3
Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium
Key facts
- Who runs it
- Mayo Clinic
- Where
- Rochester, United StatesSee the site
- Trial code
- Status
- Recruiting
- Phase
- Phase 3
- People taking part
- 400 people, planned
- Started
- 20 Dec 2024
- Planned end
- 1 Nov 2026
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Sevoflurane
- Isoflurane
- Record updated
- 16 December 2025
Who can take part
- Age
- 2 years to 7 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Pediatric patients aged 2-7 years
- Surgeries include ENT cases (i.e., tonsillectomy/adenoidectomy), ophthalmology cases (i.e., strabismus), and urology cases
- Can be outpatient or General Care inpatient procedures
- All cases must include an IV and an endotracheal tube (ETT)
Who cannot take part
- Previous history of severe emergence delirium documented by a provider (via interventions or explicitly stated)
- Severe developmental/cognitive delay (unable to make eye contact, nonverbal, or inability to interact with providers for PAED scale assessment requirements)
- TIVA cases
- No PIV in place during the case, planned PICU admission postoperatively
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 2 and 7 years old?
Where in United States
- Mayo Clinic in RochesterRochester, United StatesContact: Lindsay Warner (principal investigator)Taking people
About the trial
What the trial wants to find out
The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.
The 2 groups in the trial
- Isoflurane groupExisting treatment, for comparison
Treatment: Isoflurane
- Sevoflurane groupExisting treatment, for comparison
Treatment: Sevoflurane
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Sevoflurane/Dexmedetomidine vs. Isoflurane and Their Effects on Pediatric Emergence Delirium
- Fit questions
- Built from NCT06624592, who can take part
- Record updated
- 16 December 2025