Studying biological changes around bariatric surgery in adults with obesity
Follows adults with obesity before, during and after bariatric surgery.
Plain-language title generated from the registry record
Registry title: Nantes Bariatric Surgery Cohort
Key facts
- Where
- Nantes, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT06625762, who can take part
Where in France
- Nantes University HospitalNantes, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Nantes University Hospital
- Trial code
- NCT06625762
- Record updated
- 3 April 2026
- Original description
While current research suggests that inflammation of adipose tissue in obesity is linked to accelerated aging, it has yet to be determined in humans how this could enhance preventative and personalized medicine for obese individuals. The NBC study aims to investigate :Read full original descriptionShow less
Nantes Bariatric Surgery Cohort
While current research suggests that inflammation of adipose tissue in obesity is linked to accelerated aging, it has yet to be determined in humans how this could enhance preventative and personalized medicine for obese individuals. The NBC study aims to investigate :
1. Whether bariatric surgery is associated with changes in biological age 2. If bariatric surgery alters adipocyte dysfunction, the microbiota and biological rhythms 3. Whether changes in adipocyte dysfunction, microbiota and biological rhythms are linked to changes in biological age.
To achieve this, establishing a biocollection before, during and after bariatric surgery will be crucial in addressing these questions
Inclusion: Individuals selected for bariatric surgery (starting the BC pathway within the Nantes University Hospital bariatric unit). Inclusion criteria are those of the Bariatric Surgery program; male or female, adult over 18 years of age; BMI ≥ 35 kg/m2 with complication(s) or ≥ 40 kg/m2 with or without complication (the list of eligible complications is referenced in HAS 2024 recommendations). In the event of a change in access to bariatric surgery, this threshold could be revised without any substantial change to the protocol; having consented to their participation in the cohort; participant affiliated to or benefiting from a social security scheme.
Exclusion: Persons protected by law (guardianship or trusteeship) or deprived of their freedom,; Pregnant women (contraindication to CB) or nursing mothers.