Tests MRI scans to find non-invasive markers of fatty liver disease
Tests MRI scans to detect aggressive fatty liver disease without a liver biopsy.
Plain-language title generated from the registry record
Registry title: Exploratory Study of MRI Biomarkers of NASH
Key facts
- Where
- Angers and Rennes, FranceSee the 2 sites
Where in France
- University Hospital AngersAngers, FranceTaking people
- CHU de RennesRennes, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Angers
- Trial code
- NCT06626074
- Record updated
- 16 June 2026
- Original description
Metabolic steatosis disease (NAFLD) is a rapidly growing disease in the world, particularly in industrialized countries.Read full original descriptionShow less
Exploratory Study of MRI Biomarkers of NASH
Metabolic steatosis disease (NAFLD) is a rapidly growing disease in the world, particularly in industrialized countries.
NAFLD is defined by the presence of fatty liver disease. This is a reversible phenomenon that can be estimated by non-invasive means, such as ultrasound. Non-invasive quantification, on the other hand, requires MRI.
Nonalcoholic steatohepatitis (NASH) is the aggressive form of the disease that promotes the accumulation of fibrosis in the liver, which can progress to cirrhosis and its complications.
Currently there is no non-invasive biomarker of NASH and the diagnosis is based solely on liver biopsy.
There is therefore a need for non-invasive biomarkers of NASH in patients with steatosis to diagnose NASH without the use of liver biopsy.
Inclusion: Patient included in the SNIFF cohort of the Angers hospital where there is a suspicion of NASH requiring a biopsy for which an MRI is requested by a hepatologist as part of the initial assessment of the disease; Adult patient; Free, informed and express (oral) consent of the patient to participate in the study.
Exclusion: Person under compulsion to psychiatric care; Contraindication to MRI; Time between the establishment of the Steatosis/NASH status and the MRI greater than 3 months; Pregnant, parturient and breastfeeding woman; Person deprived of liberty by judicial or administrative decision; Person subject to a legal protection measure; Person not affiliated or not covered by a social security scheme.