AI Imaging to Predict Parkinson's Risk in Sleep Behavior Disorder
Uses AI on brain scans to predict Parkinson's in adults with REM sleep behavior disorder.
Plain-language title generated from the registry record
Registry title: Artificial Intelligence in Molecular Imaging: Predicting Parkinson's Risk in REM Sleep Behavior Disorder
Key facts
- Where
- Bern, SwitzerlandSee the site
Where in Switzerland
- Inselspital, University Clinic for Nuclear MedicineBern, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Insel Gruppe AG, University Hospital Bern
- Trial code
- NCT06629207
- Record updated
- 8 November 2024
- Original description
The study aims to systematically document the course of REM sleep behavior disorder (RBD) and investigate possible clinical and imaging biomarkers for disease progression and conversion risk to Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). The study will use artificial intelligence to analyze imaging and develop a reliable method to predict and stratify patients approaching conversion to overt a-synucleinopathy. Participants will be clinically evaluated and 2 imaging procedures will be done.Read full original descriptionShow less
Artificial Intelligence on Molecular Imaging to Predict the Risks of Parkinson's Disease for Patients With Rapid Eye Movement Sleep Behavior Disorder
The study aims to systematically document the course of REM sleep behavior disorder (RBD) and investigate possible clinical and imaging biomarkers for disease progression and conversion risk to Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). The study will use artificial intelligence to analyze imaging and develop a reliable method to predict and stratify patients approaching conversion to overt a-synucleinopathy. Participants will be clinically evaluated and 2 imaging procedures will be done.
Inclusion: Confirmed clinical iRBD diagnosis by movement disorder specialists according to the International Classification of Sleep Disorders; Written informed consent.
Exclusion: Known diagnosis of PD or other neurodegenerative disorder; Unequivocal signs of parkinsonism on examination; Narcolepsy or other known causes of RBD; Moderate to severe obstructive sleep apnea; Abnormal neurological or MRI examination.