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A Biobank Collecting Samples From People With Malignant Hypertension

Stores biological samples from adults treated for severe, dangerously high blood pressure.

Key facts

Who runs it
Centre Hospitalier de PAU
Where
Annecy, Bordeaux, Chalon-sur-Saône, Lyon, Paris, Strasbourg, Toulouse, Tours, and Valenciennes, FranceSee the 11 sites
Trial code
Registry title
Determinants of Malignant Hypertension Onset and Related Target Organ Damages: the HAMA Biobank
Status
Recruiting
People taking part
1,000 people, planned
Started
19 Mar 2026
Expected to end
1 Apr 2036
Type of study
Observational
Treatments tested
  • biobank
Record updated
22 October 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults in the HAMA cohort who have malignant hypertension, meaning very high blood pressure with serious organ damage. Blood and other samples are collected and stored.

Age
18 years or older
Sex
All sexes can join
Disease stage
Malignant hypertension: severe hypertension with severe hypertensive retinopathy, or severe hypertension with acute damage to organs caused by high blood pressure

Main reasons for not taking part

  • Refusal to take part in the HAMA bank substudy
  • Being on chronic dialysis

The registry criteria, word for word

Show all 3 criteriaShow less

Who can take part

  • patients included in the HAMA cohort with the following critera :; Malignant hypertension according to the classic definition (Severe hypertension associated with severe hypertensive retinopathy); Severe hypertension associated with acute target organ damage due to high blood pressure

Who cannot take part

  • Refusal to participate to the substudy " HAMA bank "
  • patient on chronic dialysis

Where in France

  • CH d'ANNECYAnnecy, FranceContact: Sandra JOST TURILLOTTaking people
  • CHU de BordeauxBordeaux, FranceContact: Romain BOULESTREAUTaking people
  • CH de Chalon sur SaôneChalon-sur-Saône, FranceContact: Magali LOUISTaking people
  • Hospices Civils de LyonLyon, FranceContact: Pierre Yves COURANDNot yet recruiting
  • APHP AvicenneParis, FranceContact: Marilucy LOPEZ SUBLETTaking people
  • Hôpital Européen Georges PompidouParis, FranceContact: Aurélien LORTHIOIRTaking people
  • Hôpital Paris Saint JosephParis, FranceContact: Yara HANON - ANTAKLYTaking people
  • CHU de StrasbourgStrasbourg, FranceContact: Dominique STEPHANTaking people
  • CHU de ToulouseToulouse, FranceContact: Béatrice DULY-BOUHANICKTaking people
  • CHRU de ToursTours, FranceContact: Jean Michel HALIMITaking people
  • CH de ValenciennesValenciennes, FranceContact: Claire CARTERYTaking people

About the trial

What the trial wants to find out

The HAMA bank is an initiative aimed at collecting, preparing, and storing biological samples from patients treated for malignant hypertension and included in the HAMA cohort. Conducted under CRB (ISO20387) conditions, this biobank serves as an essential resource for understanding the disease's pathophysiology, as well as for identifying novel biomarkers and therapeutic targets

Treatments tested

  • biobank

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Determinants of Malignant Hypertension Onset and Related Target Organ Damages: the HAMA Biobank
Plain-language title
A Biobank Collecting Samples From People With Malignant HypertensionGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
22 October 2026