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Relationship Program for Chinese Male Couples Where One Partner Has HIV

Tests a relationship program for Chinese male couples where one partner has HIV.

Plain-language title generated from the registry record
Registry title: We-INtervention Among Chinese HIV-serodiscordant Male Couples

Key facts

Where
Chengdu, Guangzhou, Shenzhen, and Xiamen, ChinaSee the 4 sites

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for male couples in a committed relationship where one partner is HIV-positive and the other is HIV-negative. Both partners join together.

Age
Both partners must be 18 or older.
Sex
Male only. Both partners must be male.
Disease stage
One partner is HIV-positive and the other is HIV-negative.
Biomarker or test result
One partner is HIV-seropositive and the other is HIV-seronegative.

Main reasons for not taking part

  • Either partner cannot complete the assessment because of a low education level or physical or psychological limits
  • Either partner has been diagnosed with another chronic disease, for example cancer or coronary heart disease

Read by machine on 12 November 2026.

Where in China

  • Jin Tang Six-Color Rainbow Healthcare CenterChengdu, ChinaContact: Shanzhi FengTaking people
  • Guangzhou Yuele Healthcare Service CenterGuangzhou, ChinaContact: Weizan ZhuTaking people
  • Community Always ThereShenzhen, ChinaContact: Honglin LiuTaking people
  • Fangzhouai GardenXiamen, ChinaContact: Tianqi LinTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
City University of Hong Kong
Trial code
NCT06639932
Record updated
21 January 2026
Original description
HIV-serodiscordant male couples, in which one male partner is HIV-seropositive and the other is HIV-seronegative, experience multiple risks in HIV care and prevention. As stigma often hinders such couples' access to support and services, leveraging their relational resources is crucial for optimizing their outcomes. The proposed study will assess the efficacy of the three-session We-INtervention focusing on their relationship dynamics to enhance Chinese HIV-serodiscordant male couples' health and well-being.Read full original descriptionShow less

Evaluating the Effects of the We-INtervention Among Chinese HIV-serodiscordant Male Couples in a Randomized Controlled Trial

HIV-serodiscordant male couples, in which one male partner is HIV-seropositive and the other is HIV-seronegative, experience multiple risks in HIV care and prevention. As stigma often hinders such couples' access to support and services, leveraging their relational resources is crucial for optimizing their outcomes. The proposed study will assess the efficacy of the three-session We-INtervention focusing on their relationship dynamics to enhance Chinese HIV-serodiscordant male couples' health and well-being.

A total of 160 Chinese HIV-serodiscordant male couples (320 individuals: 160 HIV-seropositive and 160 HIV-seronegative) will be randomized at a 1:1 ratio to either the intervention or control arm. In the intervention arm, the We-INtervention will be delivered to both partners of each couple separately. In the control arm, each couple will receive health information pamphlets.

Inclusion: both partners are male,; both partners are aged 18 or above,; both partners report being in a committed relationship for at least 3 months,; one partner is HIV-seropositive and the other partner is HIV-seronegative (i.e., serodiscordant couple),; both partners have disclosed their serostatus to each other, and; both partners are willing to participate in this study.

Exclusion: either partner has been diagnosed with another chronic disease (e.g., cancer and coronary heart disease); either partner is unable to complete the assessment due to a low education level or to physical or psychological constraints and.

ClinicalTrials.gov NCT06639932