Taking people in DenmarkPhase 4
A Pragmatic Trial Comparing Empagliflozin and Dapagliflozin Through Cluster Randomization Embedded in the Electronic Health Record
Key facts
- Where
- Copenhagen, Herlev, Hillerød, Holbæk, Hvidovre, Køge, Nykøbing Falster, Rønne, Roskilde, and Slagelse, DenmarkSee the 12 sites
- Phase
- Phase 4
Where in Denmark
- Bispebjerg HospitalCopenhagen, DenmarkTaking people
- RigshospitaletCopenhagen, DenmarkTaking people
- Herlev and Gentofte HospitalHerlev, DenmarkTaking people
- Steno Diabetes Center CopenhagenHerlev, DenmarkTaking people
- Nordsjællands HospitalHillerød, DenmarkTaking people
- Holbæk SygehusHolbæk, DenmarkTaking people
- Hvidovre HospitalHvidovre, DenmarkTaking people
- Sjællands UniversitetshospitalKøge, DenmarkTaking people
- Nykøbing F. SygehusNykøbing Falster, DenmarkTaking people
- Bornholms HospitalRønne, DenmarkTaking people
- Sjællands UniversitetshospitalRoskilde, DenmarkTaking people
- Slagelse SygehusSlagelse, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Herlev and Gentofte Hospital
- Trial code
- NCT06642272
- Record updated
- 18 September 2026
- Original description
The aim of this clinical trial is investigate the comparative effectiveness of empagliflozin and dapagliflozin for the treatment of diabetes, chronic kidney disease, and heart failure.Read full original descriptionShow less
The aim of this clinical trial is investigate the comparative effectiveness of empagliflozin and dapagliflozin for the treatment of diabetes, chronic kidney disease, and heart failure.
Patients who are prescribed either empagliflozin or dapagliflozin, as part of daily clinical practice at the participating sites, will be included in the study. Treatment will be randomized automatically through the electronic health record software in clusters defined by time of day.
https://www.appletreestudy.com
Inclusion: Adults aged 18 years or more.
Exclusion: Incapabability of giving informed consent; Withdrawal of informed consent.