NCT06649084Enrolling by invitation
Primary Progressive Aphasia Multicomponent Language Treatment Study
Establishing Evidence-based Multicomponent Treatment for Speech and Language in Primary Progressive Aphasia
Source: ClinicalTrials.gov · Last updated 8 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to learn if a speech-language telerehabilitation helps improve communication in people with primary progressive aphasia (PPA), a form of dementia that affects speech and language. The study will also document how acceptable and helpful the program is for both patients and their care partners. The main questions the study aims to answer are: 1. Is the telerehabilitation program feasible and acceptable for people with PPA and their care partners? 2. Do participants with PPA and care partners report satisfaction with the program? 3. Which outcome measures are most useful for evaluating changes in communication and quality of life? 4. What patterns of treatment response are seen in participants after completing the program? Researchers will test the program in a small group of participants to see how people respond. The program includes both speech-language therapy and training for care partners. Participants will: * Take part in online speech-language therapy sessions * Complete communication tasks and questionnaires before and after the program * Have regular virtual check-ins with the research team * Include their care partners in some parts of the program for training and support
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 21 (estimated)
- First submitted
- 16 Oct 2024
- Start date
- 2 May 2023
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- University of Texas at Austin
- Diseases
- Frontotemporal dementia
- NCT number
- NCT06649084
What you commit to
- Study type: Interventional
- Planned participants: 21
- From 2 May 2023 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other neurological or psychiatric diagnosis that may contribute to cognitive-linguistic deficits
- Significant, uncorrected visual or hearing impairment that would interfere with participation
- Prominent initial non-speech-language impairment (cognitive, behavioral, motoric)
Other
- Score of less than 10 on the Mini-Mental State Examination
Who the study is looking for
- Meets diagnostic criteria for Primary Progressive Aphasia (PPA; Gorno-Tempini et al., 2011)
- Scores of 10 or higher on the Mini-Mental State Examination
- Has a study partner who can consistently attend sessions
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas Coordinator of this site? Confirm its status | Austin | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.