NCT06655415Recruiting
Family Members at INcreased-risk for Developing Inflammatory Bowel Disease
Family Members at INcreased-risk for Developing Inflammatory Bowel Disease (FIND-IBD)
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
First-degree relatives of people with inflammatory bowel disease ("IBD," including Crohn's disease and ulcerative colitis) have an increased risk for developing IBD themselves. This study will follow unaffected first-degree relatives (who do not have IBD) over time to understand if their behaviors, diet, and biomarkers for IBD can help predict who gets IBD and if IBD can be prevented in these high-risk individuals. Participants will be asked once per year to complete a questionnaire and have their blood, stool, and urine collected. The anticipated length of the study (registry) is approximately 10 years or longer. Parts of this study, such as the questionnaires and stool and urine collection, may be done from home, while other parts, such as the blood draw, will need to be done from Massachusetts General Hospital.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 21 Oct 2024
- Start date
- 18 Dec 2024
- Primary completion date
- Dec 2034
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Crohn's disease, Ulcerative colitis
- NCT number
- NCT06655415
What you commit to
- Study type: Observational
- Planned participants: 50
- From 18 Dec 2024 to the primary completion date, Dec 2034
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Individuals with existing diagnoses of inflammatory bowel disease (ulcerative colitis, Crohn's disease, or IBD-unclassified)
Other
- Evidence of clinical signs or symptoms of IBD, which will be identified on pre-screening interview with the study coordinator.
Who the study is looking for
- Ability to give informed consent
- Ability to complete all study visits and study-related procedures
- Ability to understand and complete study questionnaires
- Must have at least one first-degree relative with inflammatory bowel disease (Crohn's disease, ulcerative colitis, or IBD-unclassified)
- Age ≥ 14
Age in the registry: 14 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.