Comparing two body imaging scans in people with symptomatic multiple myeloma
Compares whole body MRI with PET/CT scans in adults with multiple myeloma.
Plain-language title generated from the registry record
Registry title: Comparison Between Whole Body DWI and FDG PET/CT in Patients with Simptomatic Multiple Myeloma
Key facts
- Where
- Bologna, ItalySee the site
Where in Italy
- Policlinico S. Orsola MalpighiBologna, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Trial code
- NCT06659276
- Record updated
- 26 October 2024
- Original description
The primary objective is to evaluate the concordance of FDG PET/CT and total body DWI MRI sequences performed during staging and at the completion of therapy. Specifically, we will assess the positivity rates, both patient-based and lesion-based (total and by district), of the two methods during staging and at the completion of therapy. An interim analysis will be conducted comparing the two methods, followed by a final prognostic analysis.Read full original descriptionShow less
Whole Body DWI Sequences As Compared with Standard FDG PET/CT in Patients with Simptomatic Multiple Myeloma
The primary objective is to evaluate the concordance of FDG PET/CT and total body DWI MRI sequences performed during staging and at the completion of therapy. Specifically, we will assess the positivity rates, both patient-based and lesion-based (total and by district), of the two methods during staging and at the completion of therapy. An interim analysis will be conducted comparing the two methods, followed by a final prognostic analysis.
Inclusion: • Patients with symptomatic myeloma in the staging phase or with suspected symptomatic myeloma in the diagnostic phase; Patients who have signed the informed consent form.
Exclusion: Patients simultaneously affected by other neoplastic diseases or with a history of other neoplasms in the previous 5 years; Age < 18 years; Women who are breastfeeding or pregnant; Patients with metal implants or devices that constitute an absolute contraindication for MRI; Patients with severe claustrophobia; Patients with bone pain that prevents prolonged maintenance of the supine position.