Effect of Eccentric Exercise on Spasticity, Walking and Balance in Spastic Cerebral Palsy
Key facts
- Who runs it
- Lokman Hekim University
- Where
- Türkiye1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 42 people enrolled
- Started
- 15 Aug 2024
- Ended
- 15 Jun 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Neurodevelopmental Therapy (NDT) and Eccentric Exercise Training Group (NDT+EE)
- Neurodevelopmental Therapy (NDT)
- Record updated
- 6 January 2026
Who can take part
- Age
- 6 years to 18 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Being between the ages of 6-18 and diagnosed with spastic hemiparetic or spastic diparetic CP,
- Being at level I, II or III according to GMFCS,
- Having increased muscle tone in hip flexor, hip adductor, knee flexor, knee extensor or ankle plantar flexor muscles according to MTS,
- Giving informed consent including detailed information prepared for the study (by parent/guardian)
Who cannot take part
- Having received botox or surgery in the last 6 months
- Having a systemic disease in addition to CP
- Not signing the consent form
- Having limited cooperation regarding perception or performance of exercises required for the study
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About the trial
What the trial wants to find out
Our clinical research study is planned as a randomized controlled study and will use a stratified randomization method. The aim of this study is to investigate the effects of eccentric exercise training on spasticity, walking and balance in individuals with spastic Cerebral Palsy (CP). Individuals with spastic unilateral SP (hemiparetic) and bilateral SP (diparetic) diagnosis, Gross Motor Function Classification System (GMFCS) Level I, II and III, aged between 6-18 years will be included in the study.
The 2 groups in the trial
- Neurodevelopmental Therapy (NDT)Existing treatment, for comparison
The Neurodevelopmental Therapy (NDT) treatment program, which was determined by the physiotherapist to be individual and suitable for the needs of the cases in both groups participating in the study, will continue throughout the study, with 2 sessions per week and 40 minutes each session. The orthoses and assistive devices used by the cases will continue to be used without any changes and no changes will be made to the treatment program.
- Neurodevelopmental Therapy (NDT) and Eccentric Exercise Training Group (NDT+EE)Treatment being tested
The subjects in the study group will be applied NDT 20 minutes twice a week, each session lasting 40 minutes, and in addition, an eccentric exercise program of 20 minutes will be applied in each session. For eccentric exercise training, a functional eccentric exercise program will be applied especially for the hip flexor (m. iliopsoas, m. rectus femoris) muscle group, which is the most common and intense spasticity seen in the lower extremities, hip adductors (m. adductor magnus and minimus, m. adductor longus and brevia, m. pectineus, m. gracillis), knee flexors (m. semitendinosus, m. semimembranouzsu, m. biceps femoris) and plantar flexors (m. gastrocnemius, m. soleus and m. tibialis posterior). If the orthosis used by the individual is applied during the eccentric exercise program, it will be removed.
Treatment: Neurodevelopmental Therapy (NDT) and Eccentric Exercise Training Group (NDT+EE) and Neurodevelopmental Therapy (NDT)
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effect of Eccentric Exercise Training on Spasticity, Walking and Balance in Individuals With Spastic Cerebral Palsy
- Record updated
- 6 January 2026