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Taking people in United StatesNo phase

Individual Factors of CBT Underlying Success

Key facts

Who runs it
University of Washington
Where
Seattle, United StatesSee the site
Trial code
Status
Recruiting
People taking part
160 people, planned
Started
15 Oct 2024
Expected to end
30 Sept 2028
Type of study
Interventional
Treatments tested
  • Cognitive Behavioral Therapy
Record updated
17 February 2026

Who can take part

Age
18 years to 45 years
Sex
Women and men
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 12 criteriaShow less

Who can take part

  • Clinical sample (N=110):
  • Men and women, age 18-45
  • Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV
  • Fluent in English and willing to provide informed consent; Control sample (N=50):
  • Men and women, age 18-45
  • No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV
  • Meet criteria for low levels of anxiety (GAD-7 score of <8) and depression (PHQ-9 score <10)
  • Fluent in English and willing to provide informed consent

Who cannot take part

  • fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia)
  • Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or hypomanic episode, psychotic symptoms, traumatic brain injury, neurological disorder, pervasive developmental disorder, or attention deficit-hyperactivity disorder; active alcohol or substance use disorder in the past 6 months 4. Current use of psychotropic medications, except antidepressants taken at a stable dose for 3 months prior to study baseline 5. Previous CBT non-responder or current CBT
  • All groups:
  • Score < 80 based on WRAT5 Word Reading Subtest

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 45 years old?

Where in United States

  • University of WashingtonSeattle, United StatesContact: Randhara Kotuwelle, B.A.Taking people

About the trial

What the trial wants to find out

The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.

The group in the trial

  • Cognitive behavioral therapyTreatment being tested

    Twelve weekly sessions of individual cognitive behavioral therapy

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Contributions of Self-Focused Attention to Early Warning Indicators of Cognitive Behavioral Therapy Non-Response
Fit questions
Built from NCT06678295, who can take part
Record updated
17 February 2026