Frontlight ResearchEarly access
Taking people in United StatesNo phase
Individual Factors of CBT Underlying Success
Key facts
- Who runs it
- University of Washington
- Where
- Seattle, United StatesSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 160 people, planned
- Started
- 15 Oct 2024
- Expected to end
- 30 Sept 2028
- Type of study
- Interventional
- Treatments tested
- Cognitive Behavioral Therapy
- Record updated
- 17 February 2026
Who can take part
- Age
- 18 years to 45 years
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- Clinical sample (N=110):
- Men and women, age 18-45
- Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV
- Fluent in English and willing to provide informed consent; Control sample (N=50):
- Men and women, age 18-45
- No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV
- Meet criteria for low levels of anxiety (GAD-7 score of <8) and depression (PHQ-9 score <10)
- Fluent in English and willing to provide informed consent
Who cannot take part
- fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia)
- Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or hypomanic episode, psychotic symptoms, traumatic brain injury, neurological disorder, pervasive developmental disorder, or attention deficit-hyperactivity disorder; active alcohol or substance use disorder in the past 6 months 4. Current use of psychotropic medications, except antidepressants taken at a stable dose for 3 months prior to study baseline 5. Previous CBT non-responder or current CBT
- All groups:
- Score < 80 based on WRAT5 Word Reading Subtest
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Where in United States
- University of WashingtonSeattle, United StatesContact: Randhara Kotuwelle, B.A.Taking people
About the trial
What the trial wants to find out
The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.
The group in the trial
- Cognitive behavioral therapyTreatment being tested
Twelve weekly sessions of individual cognitive behavioral therapy
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Contributions of Self-Focused Attention to Early Warning Indicators of Cognitive Behavioral Therapy Non-Response
- Fit questions
- Built from NCT06678295, who can take part
- Record updated
- 17 February 2026