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Pharmacist-physiotherapist Collaborative Management for Early Knee Osteoarthritis

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  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
University of Alberta
Trial code
NCT06681142
Record updated
27 October 2026
Original description
Osteoarthritis (OA) is a slowly progressive chronic condition that is associated with aging and is characterized as joint pain. Individuals with early-stage OA usually do not seek medical attention. If and when they do, patients more often present to a pharmacy for over-the-counter medications.Read full original descriptionShow less

Osteoarthritis (OA) is a slowly progressive chronic condition that is associated with aging and is characterized as joint pain. Individuals with early-stage OA usually do not seek medical attention. If and when they do, patients more often present to a pharmacy for over-the-counter medications.

The investigators want to leverage community pharmacists' accessibility and scope of practice to best support patients with early knee OA. Given there are no disease-modifying treatments for OA, treatment guidelines center on patient education, self-management, and exercise, with medications playing a supporting role. Self-management is an effective strategy that provides a solid foundation for managing this progressive chronic condition and health care professionals like physiotherapists and pharmacists can help with the development and application of these skills.

Inclusion: regularly experiencing pain, aching, or stiffness in and/or around the knee for at least 1 month; complete the screening PhIT-OA questionnaire.

Exclusion: Prior total knee replacement or on the waitlist to have your knee replaced; Knee surgery within the previous 4 months; History of acute injury to knee within previous 6 months; Previous physician-diagnosed inflammatory arthritis (including this list): Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis, Lupus, Gout; Received a knee joint injection in the past 3 months or have one scheduled in the next 3 months; History of the following medications: csDMARD or bDMARD or tsDMARD, Immunosuppressive, Allopurinol or febuxostat, Colchicine; Unable to speak and read English; Unwilling or unable to visit a physiotherapist at a community physiotherapy clinic (specifically the dates and times of the partnering physiotherapy clinic); Physician diagnosed fibromyalgia; A sudden, severely painful, hot, swollen joint at any time in the past; Has completed the GLA:D Hip and Knee program at all in the past.

ClinicalTrials.gov NCT06681142