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Compares two keyhole surgery methods for central non-small cell lung cancer

Compares two minimally invasive surgeries in adults with central non-small cell lung cancer.

Key facts

Who runs it
Second Affiliated Hospital, Zhejiang University, School of Medicine
Where
Hangzhou and Shanghai, ChinaSee the 3 sites
Trial code
Registry title
Sleeve Lobectomy for Lung Cancer in Minimally Invasive Surgical Techniques
Status
Recruiting
People taking part
450 people, planned
Started
1 Mar 2025
Expected to end
31 Dec 2027
Type of study
Observational
Treatments tested
  • RATS Group
  • VATS group
Record updated
24 April 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with central lung cancer who are likely to have a sleeve lobectomy, and later confirmed non-small cell lung cancer. It compares robotic and video-assisted keyhole surgery.

Age
18 years or older
Sex
All sexes can join.
Disease stage
Suspected lung cancer likely to need sleeve lobectomy; surgery must confirm non-small cell lung cancer (NSCLC).
Earlier treatment
No history of cancer within the past 5 years.

Main reasons for not taking part

  • Cannot have surgery because of medical reasons
  • Surgery does not confirm non-small cell lung cancer
  • Had a cancer within the past 5 years
  • Follow-up data cannot be obtained
  • Refuses or withdraws consent

The registry criteria, word for word

Show all 10 criteriaShow less

Who can take part

  • Age ≥ 18 years
  • Clinically suspected lung cancer with a high likelihood of undergoing sleeve lobectomy
  • Postoperative histopathological diagnosis confirms non-small cell lung cancer (NSCLC)
  • No history of malignancy within the past 5 years
  • Signed informed consent agreeing to participate in this study

Who cannot take part

  • Unable to undergo surgical resection due to surgical contraindications
  • Postoperative pathology does not confirm non-small cell lung cancer (NSCLC), including but not limited to benign lesions, small cell lung cancer, metastatic tumors, or an insufficient or indeterminate histopathology report
  • History of malignancy within the past 5 years
  • Unable to obtain follow-up data
  • Refusal to sign the informed consent or withdrawal of consent

Where in China

  • Sir Run Run Shaw Hospital, Medical College, Zhejiang UniversityHangzhou, ChinaContact: Yuhan Zhou, M.D.Taking people
  • The Second Affiliated Hospital Zhejiang University School of MedicineHangzhou, ChinaContact: Haifeng Shen, M.D.Taking people
  • Shanghai Chest Hospital, Shanghai Jiao Tong UniversityShanghai, ChinaContact: Xinghua Cheng, M.D. Ph.D.Taking people

About the trial

What the trial wants to find out

The goal of this multicenter observational study is to evaluate the long-term survival and perioperative outcomes of sleeve lobectomy in robotic-assisted thoracic surgery (RATS) for patients with central lung cancer when compared with video-assisted thoracic surgery (VATS) approach, both of which have been already applied to these patients in minimally invasive surgical techniques as part of their regular medical care recently. The main question it aims to answer is:

Read full original descriptionShow less

Are RATS sleeve lobectomy associated with similar or even better long-term survival and perioperative outcomes for patients with central lung cancer when compared with the VATS approach?

The group in the trial

  • Lung cancer cohort of sleeve lobectomy in minimally invasive surgical approaches

    This lung cancer cohort will retrospectively identify and enroll the participants with centrally located primary NSCLC receiving bronchial sleeve resection with or without pulmonary artery angioplasty in minimally invasive approaches (RATS or VATS) between January 2015 and September 2024 from the institutional databases. The choice of minimally invasive surgical approaches depends on the willingness of the surgeons and the participants in this study.

    Treatment: RATS Group and VATS group

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Sleeve Lobectomy for Lung Cancer in Minimally Invasive Surgical Techniques: a Multicenter Cohort Study
Plain-language title
Compares two keyhole surgery methods for central non-small cell lung cancerGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
24 April 2026