Exercise training and genes in people with high blood pressure and sleep apnea
Tests exercise training in people with high blood pressure and obstructive sleep apnea.
Key facts
- Who runs it
- University of Sao Paulo General Hospital
- Where
- Brazil1 site in 1 countryChoose a country to see its sites
- Trial code
- Registry title
- Effects of Exercise Training and Genetic Factors in Hypertensive Patients with Obstructive Sleep Apnea Sleep
- Status
- Enrolling by invitation
- People taking part
- 72 people, planned
- Started
- 26 Feb 2024
- Expected to end
- 25 Feb 2028
- Type of study
- Interventional
- Treatments tested
- Exercise training
- Record updated
- 14 November 2024
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people with high blood pressure and obstructive sleep apnea who do not exercise. Obstructive sleep apnea means breathing stops again and again during sleep.
- Age
- 45 Years to 70 Years
- Sex
- All sexes can join.
- Disease stage
- High blood pressure with obstructive sleep apnea of more than 15 events per hour of sleep, seen on an overnight sleep test (polysomnography).
Main reasons for not taking part
- Severe heart or blood vessel disease
- Severe lung or breathing disease
- Severe kidney disease
- Severe neuropsychiatric disease
The registry criteria, word for word
Show all 3 criteriaShow less
Who can take part
- sedentary,
- Hipertensive patients
Who cannot take part
- Severe cardiovascular, respiratory, renal or severe neuropsychiatric disease
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 45 and 70 years old?
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The objective is to investigate the effects of exercise training in hypertensive individuals with obstructive sleep apnea (OSA) in neurovascular control taking into account genetic factors. Seventy-two hypertensive patients with OSA >15 events/hour of sleep revealed by nocturnal polysomnography will be randomized into a control or physical training group. All will be evaluated for the T786 genotypes of the eNOS gene gene. The study will investigate the effect of the exercise program on vascular control in different alleles of the T786 genotypes of the eNOS gene.
The group in the trial
- OSA training groupTreatment being tested
The training group will be analised compared the effects of exercise on vascular function in different polimorphic aleles.
Treatment: Exercise training
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effects of Exercise Training on Neurovascular Control, Endothelial Function, Cognitive Functioning and Genetic Factors in Hypertensive Patients with Obstructive Sleep Apnea Sleep
- Plain-language title
- Exercise training and genes in people with high blood pressure and sleep apneaGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Fit questions
- Built from NCT06687863, who can take part
- Record updated
- 14 November 2024