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Studying music engagement in people with Alzheimer's or Parkinson's disease

Compares everyday music habits in older adults with Alzheimer's, Parkinson's, or no disease.

Key facts

Who runs it
University Hospital, Montpellier
Where
Montpellier, FranceSee the 3 sites
Trial code
Registry title
Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease
Status
Recruiting
People taking part
120 people, planned
Started
4 Feb 2025
Planned end
1 Dec 2025
Type of study
Interventional, 3 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • neuropsychologist interview
  • questionnaire
Record updated
19 March 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people aged 60 or older with early-stage Alzheimer's disease or Parkinson's disease, and healthy older people, who live at home with a relative and speak French.

Age
60 years and older
Sex
All sexes can join.
Disease stage
Probable Alzheimer's disease confirmed by biological diagnosis, or idiopathic Parkinson's disease. For both, MMSE of 20 or higher.
Biomarker or test result
Biological diagnosis of probable Alzheimer's disease (NINCDS-ADRDA criteria).

Main reasons for not taking part

  • Other known brain or nerve diseases (such as epilepsy) or psychiatric disorders (chronic psychosis)
  • History of stroke or head injury
  • Unstable medical condition (cancer)
  • Cannot read or write, or has hearing loss without hearing aids
  • Person under legal protection or deprived of liberty

The registry criteria, word for word

Show all 20 criteriaShow less

Who can take part

  • General inclusion criteria:
  • 60 years and older
  • French-speaking and volunteering for the study
  • Living at home with a relative; Alzheimer's disease inclusion criteria:
  • Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984)
  • MMSE greater than or equal to 20
  • Diagnosis of Idiopathic Parkinson's disease
  • MMSE greater than or equal to 20

Who cannot take part

  • No known neurological pathologies (epilepsy and other non-degenerative CNS diseases) or psychiatric disorders (chronic psychosis and psychotic episodes)
  • Autistic disorders
  • History of stroke or head trauma
  • Unstable medical condition (cancer)
  • Hearing impairment without hearing aids
  • Subject unable to read and/or write
  • Refusal of consent after information
  • Persons unable to give consent, research carried out in emergency situations, etc.)
  • Non-affiliation with a social security scheme
  • Person deprived of liberty (by judicial or administrative decision, or forced hospitalization)
  • Person under legal protection (guardianship, curatorship, legal protection)
  • Person participating in another research project with an exclusion period still in progress

Where in France

  • CHU de Montpellier - CEPMoMontpellier, FranceContact: Mahmoud CHARIF, MDTaking people
  • CHU de Montpellier - CMRRMontpellier, FranceContact: Karim BENNYS, MDNot yet recruiting
  • Montpellier Seniors' AssociationMontpellier, FranceContact: Mikaël Guenguelou, PhDNot yet recruiting

About the trial

What the trial wants to find out

The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects.

Read full original descriptionShow less

The main questions it aims to answer are:

1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects. 2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up.

Participants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including :

* A semi-structured interview to check the participants eligibility and gather demographic data. * Neuropsychological tests and questionnaires will then be administered. * A relative of the study participant will help complete questionnaires.

The 3 groups in the trial

  • patient with early-onset Alzheimer's disease (AD)Treatment being tested

    patients followed up at the Centre Mémoire de Ressources et de Recherche (CMRR) of Montpellier, over 60 with Alzheimer's disease who have cognitive impairment based on an MMSE (Mini Mental State Examination) ≥ 20 and live at home with a relative

    Treatment: neuropsychologist interview and questionnaire

  • patients with parkinson's disease (PD)Existing treatment, for comparison

    patients followed up at the Center Expert Parkinson of Montpellier (CEPMo), over 60 with Parkinson's disease who have cognitive impairment based on an MMSE (Mini Mental State Examination) ≥ 20 and live at home with a relative

    Treatment: neuropsychologist interview and questionnaire

  • Healthy controlExisting treatment, for comparison

    Subjects aged over 60, with no known neurodegenerative disease, living at home with a relative in the Hérault département.

    Treatment: neuropsychologist interview and questionnaire

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Observational Pilot Study of Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease. What Are the Effects of Mnestic or Hedonic Impairment on Emotion, Reminiscence and Musical Enjoyment
Plain-language title
Studying music engagement in people with Alzheimer's or Parkinson's diseaseGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
19 March 2025