Multimodal Biocollection Linked to the French Register of Intracranial Aneurysms

Who can take part

• Any adult patient consulting for a definite and typical bifurcation AIC authenticated on MRI and/or cerebral arteriography
• Aneurysm discovered less than a year ago, with initial imaging (MRI and/or CTA and DSA) available
• Written consent obtained for study participation
• Patient covered by a social security plan
• Index case: Any adult patient consulting for a definite and typical bifurcation ICA presenting at least one other case with ICA related (child, parent, brother, sister) detected by MRI with at least one Time of Flight (TOF) sequence
• Family relatives: children, parents, brothers, sisters, of legal age, of patients with a family history of definite, typical bifurcation AIC (≥ 4 affected), Screening to be performed using MRI with at least a Time of Flight (TOF) sequence
• Written consent to participate in the study
• Patient and relatives covered by a social security plan

Who cannot take part

• Syndromic diagnosis known to cause ICA: Marfan syndrome, OSA with SMAD 3, Elhers Danlos syndrome type II and IV, Autosomal Dominant Cystic Fibrosis, Moya-Moya syndrome
• AIC with : Dissecting or fusiform, Associated with arteriovenous malformation, Blister-like, Mycotic
• Cerebral white matter pathology detected on MRI evoking : Col4a1 mutation
• Patient under guardianship or conservatorship
• Person under court protection
• Contraindication to an MRI scan