Tests genistein, a dietary supplement, in adults after a heart attack
Tests whether genistein lowers triglycerides and inflammation in adults after heart attack.
Plain-language title generated from the registry record
Registry title: Evaluating Metabolic and Anti-inflammatory Effect of Genistein on Post-myocardial Infarction Patients
Key facts
- Where
- Taipei, TaiwanSee the site
Where in Taiwan
- National Taiwan University HospitalTaipei, TaiwanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Taiwan University Hospital
- Trial code
- NCT06689566
- Record updated
- 7 August 2025
- Original description
The goal of this clinical trial is to learn if genistein works to provide a beneficial effect to show lipid lowering effect and anti-inflammatory effects and slow the progression of atherosclerosis in post-myocardial infarction adults. It will also learn about the safety of genistein. The main questions it aims to answer are:Read full original descriptionShow less
Evaluating Metabolic and Anti-inflammatory Effect of Genistein on Post-myocardial Infarction Patients
The goal of this clinical trial is to learn if genistein works to provide a beneficial effect to show lipid lowering effect and anti-inflammatory effects and slow the progression of atherosclerosis in post-myocardial infarction adults. It will also learn about the safety of genistein. The main questions it aims to answer are:
Does genistein lower triglyceride in participants? What medical problems do participants have when taking genistein? Researchers will compare the baseline, under treatment and washout period triglyceride, hsCRP to see if genistein works to decrease inflammation.
Participants will:
Take genistein every day for 3 months with a fixed dose manner. Afterwards, there will be 3 months washout period.
Visit the clinic once every month for checkups and tests. Keep a diary of their symptoms.
Inclusion: Written informed consent; Age ≥ 18 years; History of spontaneous myocardial infarction at least 28 days before recruitment; hsCRP ≥ 0.1 mg/dL; BMI ≥ 27.
Exclusion: Patients with prior history of carotid angioplasty, stenting, or carotid atherectomy; Major non-cardiac surgical or endoscopic procedure within past 6 months; Symptomatic patients with Class IV heart failure (HF) (New York Heart Association [NYHA]; Uncontrolled hypertension; Uncontrolled diabetes; History or evidence of active tuberculosis (TB) infection; Active cancer under treatment; Pregnant or nursing (lactating) women; Women of child-bearing potential; Planned coronary revascularization (PCI or CABG); BMI > 40 kg/m2.