Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
Key facts
- Where
- Kelowna and Vancouver, CanadaSee the 2 sites
- Phase
- Phase 1/2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 19 and 65 years old?
Source: NCT06691165, who can take part
Where in Canada
- UBC OkanaganKelowna, CanadaContact: Scott Thrall, MScTaking people
- International Collaboration on Repair Discoveries (ICORD)Vancouver, CanadaContact: Scott Thrall, MScTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Glen Foster
- Trial code
- NCT06691165
- Record updated
- 18 November 2025
- Original description
This study examines the effects of low oxygen therapy (LOT) on the stability of 24-hour blood pressure in persons with chronic cervical spinal cord injury.Read full original descriptionShow less
Low Oxygen Therapy as a Cardiac Treatment for Improving 24-hour Blood Pressure Stability in Spinal Cord Injury
This study examines the effects of low oxygen therapy (LOT) on the stability of 24-hour blood pressure in persons with chronic cervical spinal cord injury.
This study will examine if brief episodes of breathing lower oxygen, termed low oxygen therapy (LOT), which has been shown to enhance autonomic nervous system activity, can improve blood pressure stability in individuals with spinal cord injury. The research team will assess 24-hour blood pressure, as well as cardiac, vascular, and autonomic function before and after a 4-day LOT treatment intervention. This study will advance current understanding of treatments to mitigate cardiovascular disease risk in people with spinal cord injuries.
Inclusion: Are between the ages of 19-65; Living with a chronic cervical (at or above T1) spinal cord injury of at least one year; Are fluent in english.
Exclusion: Additional concurrent neurological conditions (e.g., multiple sclerosis, Parkinson disease, stroke or brain injury); Uncontrolled cardiovascular or pulmonary disease; History of seizure disorders; High-cervical injuries requiring ventilator assistance to breathe will be excluded on account of the necessity of the facemask for the delivery of hypoxia; Unhealed fracture, contracture, or pressure sore that might interfere with participants' ability to complete the protocol; Severe neuropathic pain; Severe recurrent autonomic dysreflexia; Known pregnancy.