The Impact of Attentive System on Sleep Reactivity
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Trial details
- Who runs it
- IRCCS San Raffaele
- Trial code
- NCT06694818
- Record updated
- 13 October 2026
- Original description
Sleep Reactivity is defined as the degree to which a given amount of stress disrupts the sleep system, and it is consistent over time and across different type of stimuli. Sleep reactivity is a normal phenomenon under a certain threshold, but when it exceeds physiological threshold, this can lead to sleep disturbances that persist even following the removal of the stressor. Indeed, higher levels of sleep reactivity are associated to sleep quality depletion (i.e., increased sleep latency, reduced sleep efficiency and increased sleep fragmentation). The contribution of sleep reactivity in insomnia could be also related to altered (rapid eyes movement (REM)) REM sleep, since it plays a fundamental role in the elaboration of emotional and stressful stimuli, promoting a readjustment of the cognitive-emotional system. Hence, an alteration of REM after a stressor may prevent its proper processing and promote the disorder.Read full original descriptionShow less
The Impact of Attentive System on Sleep Reactivity: a Study With a Participant-applied Electroencephalography in the Home Environment
Sleep Reactivity is defined as the degree to which a given amount of stress disrupts the sleep system, and it is consistent over time and across different type of stimuli. Sleep reactivity is a normal phenomenon under a certain threshold, but when it exceeds physiological threshold, this can lead to sleep disturbances that persist even following the removal of the stressor. Indeed, higher levels of sleep reactivity are associated to sleep quality depletion (i.e., increased sleep latency, reduced sleep efficiency and increased sleep fragmentation). The contribution of sleep reactivity in insomnia could be also related to altered (rapid eyes movement (REM)) REM sleep, since it plays a fundamental role in the elaboration of emotional and stressful stimuli, promoting a readjustment of the cognitive-emotional system. Hence, an alteration of REM after a stressor may prevent its proper processing and promote the disorder.
In order to, investigate this relationship this project aims to manipulate sleep reactivity to assess the differences between insomniacs and healthy controls, taking into account their attentional shifting performance and focusing on non-REM and REM sleep alterations.
Inclusion: Subjects, both male and female; aged over 18 and under 65; Ability to understand and sign the informed consent.
Exclusion: Subjects suffering from diagnosticated sleep disorders; Subjects suffering from severe or degenerative neurological diseases; Subjects unable to read, understand, or correctly complete the procedures required by the study; Subjects suffering from substance addiction; Subjects who exceed the clinical cut-off for anxiety and/or depression symptoms; Pregnancy.