Testing a Brain Implant That Detects Seizures in People With Epilepsy
Tests whether a deep brain stimulator can detect seizures in adults with drug-resistant epilepsy.
Plain-language title generated from the registry record
Registry title: Thalamus Seizure Detection With a Deep Brain Stimulator System
Key facts
- Where
- Rochester, United StatesSee the site
Where in United States
- Mayo Clinic in RochesterRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT06700356
- Record updated
- 13 July 2026
- Original description
The purpose of this study is to determine the feasibility of chronic ambulatory thalamus seizure detection. The sensitivity, specificity, and false alarm rate of thalamus seizure detection will be calculated using recordings from a deep brain stimulation system, assessed relative to concurrent gold-standard video-EEG monitoring collected in the in-patient setting (epilepsy monitoring unit), in 5 patients with drug resistant epilepsy.Read full original descriptionShow less
Seizure Detection With a Deep Brain Stimulation System
The purpose of this study is to determine the feasibility of chronic ambulatory thalamus seizure detection. The sensitivity, specificity, and false alarm rate of thalamus seizure detection will be calculated using recordings from a deep brain stimulation system, assessed relative to concurrent gold-standard video-EEG monitoring collected in the in-patient setting (epilepsy monitoring unit), in 5 patients with drug resistant epilepsy.
Inclusion: Participants must meet all of the inclusion criteria to participate in this study:; 18 years of age and older; Implanted with a clinical DBS system for epilepsy with brain recording capabilities (Medtronic Percept™ DBS); Subject or legally authorized representative is able to understand study procedures and to comply with them for the entire length of the study.
Exclusion: Current drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements; Health status or any clinical conditions (e.g., life expectancy, co-existing disease) that, in the opinion of the site investigator, would pose undue risk to undergo epilepsy monitoring unit evaluation for the purpose of seizure characterization; All candidates meeting any of the exclusion criteria at baseline will be excluded from study participation:; Women will verify not pregnant, and if applicable, have urine pregnancy test; Inability or unwillingness of individual or legal guardian/representative to give written informed consent.