Early access
Sign in
Taking peopleNo phase

Body measurement called phase angle and recovery after knee replacement for knee osteoarthritis

Looks at whether phase angle relates to recovery after knee replacement in osteoarthritis.

Key facts

Who runs it
Yonsei University
Where
South Korea1 site in 1 countryChoose a country to see its sites
Trial code
Registry title
Comparison of Functional Recovery After Total Knee Arthroplasty Between Low Phase Angle and High Phase Angle Group
Status
Recruiting
People taking part
200 people, planned
Started
13 Sept 2024
Planned end
23 Sept 2025
Type of study
Observational, 2 groups
Record updated
7 February 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people aged 55 and over with knee osteoarthritis who plan to have a total knee replacement. It compares recovery between people with a low and a high phase angle, a body measure taken with a painless electrical test.

Age
55 years and over
Sex
All
Disease stage
Knee osteoarthritis, confirmed by medical history, physical exam and X-rays, with a total knee replacement planned. The summary calls it end-stage.
Earlier treatment
People who had any knee surgery within one year cannot join.
Biomarker or test result
Phase angle is measured before surgery. Above 4.95 for males or 4.35 for females counts as the high group. Below these values counts as the low group.

Main reasons for not taking part

  • Walking problems caused by nerve or brain disorders such as Parkinson disease, stroke or dementia
  • Severe heart, lung or muscle and bone disorders that limit thigh muscle strength and physical function
  • Knee osteoarthritis from other causes, such as rheumatic or traumatic arthritis
  • Any knee surgery within one year
  • Important medical findings that make the researchers judge that the person should not take part

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Individuals aged 55 and over (based on the age on their national ID at the time of consent)
  • Individuals diagnosed with knee OA based on medical history, physical examination, and radiographic assessments
  • Individuals who plan to perform total knee arthroplasty

Who cannot take part

  • Individuals with gait disturbance due to neurologic disorders such as Parkinson disease, stroke and dementia
  • Individuals with severe cardiac, pulmonary, or musculoskeletal disorders that limited quadriceps strength and physical function
  • Individuals with a history of any knee surgery within one year
  • Individuals with knee osteoarthritis due to secondary causes such as rheumatic or traumatic arthritis
  • Individuals considered clinically unsuitable for the study by the researchers or person in charge based on significant medical findings

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

The goal of this observational study is to compare the functional outcome of patients with end-stage knee osteoarthritis (OA) before and after total knee arthroplasty based on the phase angle level.

Read full original descriptionShow less

The main questions it aims to answer are:

* Do patients with low phase angle show worse functional recovery after total knee arthroplasty compared to those with high phase angle? * Is postoperative physical function associated with preoperative phase angle level?

Researchers will compare postoperative physical function and muscle strength between the low and high phase angle groups to determine whether a low phase angle is associated with poorer functional recovery.

Participants will:

Perform physical function tests, isokinetic strength assessments, and bioelectrical impedance analysis before and three months after surgery.

The 2 groups in the trial

  • high PhA

    * Patients diagnosed with knee osteoarthritis and scheduled for total knee arthroplasty. * Among these, patients are classified into the high PhA group if their preoperative PhA is above 4.95 for males or 4.35 for females

  • low PhA

    * Patients diagnosed with knee osteoarthritis and scheduled for total knee arthroplasty. * Among these, patients are classified into the low PhA group if their preoperative PhA is below 4.95 for males or 4.35 for females

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Association Between Phase Angle and Functional Recovery After Total Knee Arthroplasty
Plain-language title
Body measurement called phase angle and recovery after knee replacement for knee osteoarthritisGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 14 November 2026.
Record updated
7 February 2025